Results 111 to 120 of about 700,206 (362)

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

open access: yesMolecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam   +9 more
wiley   +1 more source

Replacement Of The Interocclusal Space Lost After Preparatıon Wıth An Orthodontıc Applıcatıon

open access: yesTurkish Journal of Orthodontics, 1988
Interocclusal space achieved by the preparation of the teeth for the fixed prosthetic restorations could be lost with the extrusion of those teeth when a considerable elapse of time happened to be between the preparation of the teeth and the cementation ...
Hakan N. İşcan   +2 more
doaj   +1 more source

Intrusive and Non-Intrusive Load Monitoring (A Survey)

open access: yesLatin-American Journal of Computing, 2015
There is not discussion about the need of energy conservation, it is well known that energy resources are limited moreover the global energy demands will double by the end of 2030, which certainly will bring implications on the environment and hence to all of us.
openaire   +2 more sources

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

Root Resorptıon Durıng Bıcuspıd Intrusıon Wıth Varyıng Force Magnıtudes

open access: yesTurkish Journal of Orthodontics, 1996
This study was carried out on 14 upper first premolars the extractions of which were planned as a part of orthodontic treatment. Of 14 teeth, 10 formed the test group and 4, the control group. Three of the test teeth were intruded with a continuous force
Nazan Küçükkeleş   +2 more
doaj   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

open access: yesMolecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim   +8 more
wiley   +1 more source

IDSGAN: Generative Adversarial Networks for Attack Generation against Intrusion Detection

open access: yes, 2019
As an important tool in security, the intrusion detection system bears the responsibility of the defense to network attacks performed by malicious traffic.
Lin, Zilong, Shi, Yong, Xue, Zhi
core  

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