Results 51 to 60 of about 571,931 (308)

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Time Enough - Consequences of Human Microchip Implantation [PDF]

open access: yes, 1997
Dr. Ramesh argues that microchip implantation is both possible and, for some purposes, desirable and suggests that now is the time to consider strategies for preventing potentially grievous intrusion into personal ...
Ramesh, Elaine M.
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Periodontal and Periapical Responses to Mandibular Incisor Intrusion: Conventional Method Vs. Bone Anchorage

open access: yesTurkish Journal of Orthodontics, 2011
Aim:To investigate the gingival and periapical side effects of mandibular incisor intrusion using mini-implants and to compare these with those of a conventional mandibular incisor intrusion mechanic, the utility arch.Subjects and Methods:26 deep bite ...
Esen Aydoğdu   +4 more
doaj   +1 more source

Association Rule Mining Frequent-Pattern-Based Intrusion Detection in Network [PDF]

open access: diamond, 2022
S. Sivanantham   +3 more
openalex   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Intrusion of Dacron Sutures and A Recurrent Vitreous Hemorrhage: Rare Complication of Scleral Buckle

open access: yesDelhi Journal of Ophthalmology, 2020
We present a case of intrusion of a Dacron suture 8 years after scleral buckling surgery. Though rare, scleral buckle has to be removed if it is associated with complications like intrusion or extrusion, infection, or anterior segment ischemia.
Jignesh Manshibhai Gala, Raja Narayanan
doaj   +1 more source

Efficient classification using parallel and scalable compressed model and Its application on intrusion detection

open access: yes, 2014
In order to achieve high efficiency of classification in intrusion detection, a compressed model is proposed in this paper which combines horizontal compression with vertical compression.
Chen, Tieming   +3 more
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

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