Results 41 to 50 of about 30,179 (295)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

D-Type Iterative Learning Control for Open Container Motion System With Sloshing Constraints

open access: yesIEEE Access, 2021
In this paper, the iterative learning control (ILC) problem is investigated for the motion system of an open container with sloshing constraints in industrial fluid packaging.
Guang Li, Li Hou, Yong Lu
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Convergence to scale-invariant Poisson processes and applications in Dickman approximation

open access: yes, 2020
We study weak convergence of a sequence of point processes to a scale-invariant simple point process. For a deterministic sequence (zn)n∈N of positive real numbers increasing to infinity as n→∞ and a sequence (Xk)k∈N of independent non-negative integer ...
Bhattacharjee, Chinmoy, Molchanov, Ilya
core   +1 more source

Invariant Statistical Convergence of Sequences of Sets with respect to a Modulus Function

open access: yesAbstract and Applied Analysis, 2014
We introduce and study the concept of invariant convergence for sequences of sets with respect to modulus function f and give some inclusion relations.
Nimet Pancaroglu, Fatih Nuray
doaj   +1 more source

Invariance-Like Theorems and “lim inf” Convergence Properties [PDF]

open access: yesIEEE Transactions on Automatic Control, 2016
Several theorems, inspired by the Krasovskii-LaSalle invariance principle, to establish “lim inf” convergence results are presented in a unified framework. These properties are useful to “describe” the oscillatory behavior of the solutions of dynamical systems. The theorems resemble “lim inf” Matrosov and Small-gain theorems and are based on a “lim inf”
Giordano Scarciotti   +2 more
openaire   +3 more sources

A Q‐Learning Algorithm to Solve the Two‐Player Zero‐Sum Game Problem for Nonlinear Systems

open access: yesInternational Journal of Adaptive Control and Signal Processing, Volume 39, Issue 3, Page 566-581, March 2025.
A Q‐learning algorithm to solve the two‐player zero‐sum game problem for nonlinear systems. ABSTRACT This paper deals with the two‐player zero‐sum game problem, which is a bounded L2$$ {L}_2 $$‐gain robust control problem. Finding an analytical solution to the complex Hamilton‐Jacobi‐Issacs (HJI) equation is a challenging task.
Afreen Islam   +2 more
wiley   +1 more source

Conditions for convergence of the fundamental matrix of linear time-invariant time-delayed singular systems

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2002
In the introductory part of this paper the so-called general Bromwich-Wagner's theorem has been generalized. Throughout the main part of the paper, an attempt has been made to derive conditions for convergence of the fundamental matrix of linear time ...
Branko Saric
doaj   +1 more source

Adaptive Observer for Coupled Wave PDE and Infinite ODE With Sampled Data and Unknown Input: Application to Brain Hemodynamics Estimation

open access: yesInternational Journal of Adaptive Control and Signal Processing, EarlyView.
This article proposes a convergent adaptive observer for a damped wave PDE and an infinite‐dimensional ODE coupled in cascade using sampled‐in‐space ODE state measurements. The proposed observer estimates the distributed states of the PDE and ODE along with unknown PDE parameters and spatial input.
Zehor Belkhatir   +2 more
wiley   +1 more source

On Positive Recurrence of the Mn/GI/1/ Model

open access: yesMathematics, 2023
Positive recurrence for a single-server queueing system is established under generalized service intensity conditions, without the assumption of the existence of a service density distribution function, but with a certain integral type lower bound as a ...
Alexander Veretennikov
doaj   +1 more source

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