Results 81 to 90 of about 46,005 (268)

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Enhanced fingerprint classification through modified PCA with SVD and invariant moments

open access: yesFrontiers in Artificial Intelligence
This research introduces a novel MOMENTS-SVD vector for fingerprint identification, combining invariant moments and SVD (Singular Value Decomposition), enhanced by a modified PCA (Principal Component Analysis).
Ala Balti   +5 more
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Homotopies using conformal transformation with invariant total normal twist

open access: yesLe Matematiche, 1999
The aim of this paper is to detect a homotopy to a spherical curve with invariant total normal twist 0. Also, we use conformal transformation to prove a theorem that for any immersed closed C^3 -curve c in the Euclidean 3-space E^3 with vanishing total ...
El-Said R. Lashin, Tarek F. Mersal
doaj  

Global invariants of paths and curves for the group of orthogonal transformations in the two-dimensional Euclidean space

open access: yesAnalele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2019
In this paper, for the orthogonal group G = O(2) and special orthogonal group G = O+(2) global G-invariants of plane paths and plane curves in two-dimensional Euclidean space E2 are studied.
Khadjiev Djavvat, Ören İdris
doaj   +1 more source

Explicit travelling waves and invariant algebraic curves

open access: yesNonlinearity, 2015
In this paper we introduce a precise definition of algebraic traveling wave solution for general n-th order partial differential equations. All examples of explicit traveling waves known by the authors fall in this category. Our main result proves that algebraic traveling waves exist if and only if an associated n- dimensional first order ordinary ...
Gasull, Armengol, Giacomini, Hector
openaire   +4 more sources

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Robust image hashing using SIFT feature points and DWT approximation coefficients

open access: yesICT Express, 2018
This study proposes a robust hashing method using scale-invariant feature transform (SIFT) features points and discrete wavelet transform (DWT) approximation coefficients for image authentication.
Lokanadham Naidu Vadlamudi   +2 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

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