Results 111 to 120 of about 131,275 (304)

A nonparametric test of exogeneity [PDF]

, 2004
This paper is concerned with inference about a function g that is identified by a conditional moment restriction involving instrumental variables. The function is nonparametric. It satisfies mild regularity conditions but is otherwise unknown. The paper
Richard Blundell, Joel L. Horowitz, Blundell, R., Horowitz, Joel, Horowitz, J., Blundell, Richard W.   +5 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

On constant higher order mean curvature hypersurfaces in Hn×R ${\mathbb{H}}^{n}{\times}\mathbb{R}$

Advanced Nonlinear Studies
We classify hypersurfaces with rotational symmetry and positive constant r-th mean curvature in Hn×R ${\mathbb{H}}^{n}{\times}\mathbb{R}$ . Specific constant higher order mean curvature hypersurfaces invariant under hyperbolic translation are also ...
Nelli Barbara, Pipoli Giuseppe, Russo Giovanni   +2 more
doaj   +1 more source

Exposed points of left invariant means [PDF]

Pacific Journal of Mathematics, 1986
Let S be a left amenable semigroup and let ML(S) be the set of left invariant means on the Banach space of all bounded functions on S with the usual sup-norm. The author proves the following results concerning exposed points of ML(S): (1) ML(S) has exposed points iff S has finite left ideals.
openaire   +3 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Ideal Convergent Sequence Spaces with Respect to Invariant Mean and a Musielak-Orlicz Function Over n-Normed Spaces

International Journal of Analysis and Applications, 2018
In the present paper we defined I-convergent sequence spaces with respect to invariant mean and a Musielak-Orlicz function M = (M_k) over n-normed spaces.
Sunil K. Sharma
doaj   +2 more sources

Obtaining Arbitrary Prescribed Mean Field Dynamics for Recurrently Coupled Networks of Type-I Spiking Neurons with Analytically Determined Weights

Frontiers in Computational Neuroscience, 2016
A fundamental question in computational neuroscience is how to connect a network of spiking neurons to produce desired macroscopic or mean field dynamics. One possible approach is through the Neural Engineering Framework (NEF).
Wilten eNicola, Bryan eTripp, Matthew eScott   +2 more
doaj   +1 more source

Mean propagation velocity of multiphoton wave-packet states with nonzero Lorentz-invariant mass

, 2020
The concept of Lorenz invariant mass and mean propagation velocity have been investigated in detail for various multiphoton wave-packet states of light.
S. V. Vintskevich (17516589), D. A. Grigoriev (17516592)   +1 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Equipartition field strength on the sunspot boundary

Astronomy & Astrophysics
Context. A recent case study of a long-lived sunspot confirmed earlier observational indications that the outer boundary of sunspots is defined by an invariant value of the magnetic field strength.
Korda D., Jurčák J., Bello González N., Schmassmann M.   +3 more
doaj   +1 more source