Results 61 to 70 of about 805,934 (287)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Cluster Dynamical Mean Field Theories

, 2003
Cluster Dynamical Mean Field Theories are analyzed in terms of their semiclassical limit and their causality properties, and a translation invariant formulation of the cellular dynamical mean field theory, PCDMFT, is presented. The semiclassical limit of
A. Georges, A. Schiller, A.I. Lichtenstein, B.G. Nickel, C.J. Bolech, G. Biroli, G. Biroli, G. Kotliar, G. Kotliar, G. Zarand, J. Rammer, J.L. Smith, L.V. Keldysh, M.H. Hettler, O. Parcollet, Q. Si, R. Kikuchi, R. Mills, R. Mills, S. Biermann, S. Okamoto, S. Pankov, S. Savrasov, T. Maier, T. Morita, T.A. Maier, V. Dobrosavljevic, V. Dobrosavljevic   +27 more
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Calibration of the depth invariant algorithm to monitor the tidal action of Rabigh City at the Red Sea Coast, Saudi Arabia

Open Geosciences, 2020
Rabigh is a thriving coastal city located at the eastern bank of the Red Sea, Saudi Arabia. The city has suffered from shoreline destruction because of the invasive tidal action powered principally by the wind speed and direction over shallow waters ...
Aljahdali Mohammed H., Elhag Mohamed
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

A generalization and an application of the arithmetic–geometric mean inequality for the Frobenius norm

Journal of Inequalities and Applications, 2018
Recently, Kittaneh and Manasrah (J. Math. Anal. Appl. 361:262–269, 2010) showed a refinement of the arithmetic–geometric mean inequality for the Frobenius norm. In this paper, we shall present a generalization of Kittaneh and Manasrah’s result. Meanwhile,
Xuesha Wu
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Moving-Object Tracking Algorithm Based on PCA-SIFT and Optimization for Underground Coal Mines

IEEE Access, 2019
In view of the complex and changeable environment in underground coal mines, an improved algorithm based on the principal component analysis-scale invariant feature transform (PCA-SIFT) and mean shift is proposed to address the issues for which existing ...
Jiang Dai-Hong, Dai Lei, Li Dan, Zhang San-You   +3 more
doaj   +1 more source

Invariant Tests for Means with Covariates

The Annals of Statistics, 1980
We consider the problem of testing a hypothesis about the means of a subset of the components of a multivariate normal distribution with unknown covariance matrix, when the means of a second subset (the covariates) are known. Because of the possible correlation between the two subsets, information provided by the second subset can be useful for ...
Marden, John, Perlman, Michael D.
openaire   +2 more sources