Results 51 to 60 of about 808,546 (198)

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Empleo del modelo animal en la formación en endoscopia diagnóstica y terapéutica de la vía biliar

Educación Médica
Objetivo. Mostrar nuestra experiencia en la formación en endoscopia terapéutica de la vía biliar en modelo animal. Materiales y métodos. Esta actividad formativa tiene una duración de 13 horas y comienza iniciando al alumno en las diferencias anatómicas ...
J. Usón-Gargallo, F.M. Sánchez-Margallo, F. Soria-Gálvez, J. Boix-Valverde, M. Fernández-Bermejo, R. Latorre-Reviriego, S. Climent-Peris, V. Tejedo-Grafía   +7 more
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Historias de gringos y campesinos: una revisita a la ocupación estadunidense de la República Dominicana, 1916-1924

Secuencia, 2003
Una de las repercusiones de la ocupación militar de la República Dominicana por los Estados Unidos entre 1916 y 1924 fue la activación de diversos movimientos campesinos. Cada uno de estos movimientos contó con su propia dinámica y operó en un escenario
Pedro L. San Miguel
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Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

LA INTERVENCIÓN COMO ESTRATEGIA PARA LA UNIDAD DEL PROLETARIADO: Los anarquistas del Partido Liberal Mexicano

Revista de Historia Americana y Argentina, 2019
Los anarquistas del PLM consideraban la invasión extranjera como parte de una estrategia para generar la revolución mundial. Desde sus escritos afirmaron que la expropiación de la tierra y de los medios de producción se ...
Marco Antonio Samaniego López
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Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Nefrectomía Laparoscópica por Hidronefrosis Presentación de 1 caso y Revisión del Tema

Revista Colombiana de Cirugía, 1993
Se presenta 1 caso de resección completa de un riñón hidronefrótico gigante mediante acceso laparoscópico en una mujer de 28 años con una estenosis pieloureteral izquierda y atrofia renal severa. La evolución posquirúrgica fue excelente.
Carlos Hernando Morales Uribe, Juan Gonzalo Aristizábal, Gustavo Escobar, Carlos Mario Salinas , Juan Manuel Sierra, Santiago Sierra, Adolfo León Uribe, Juan José Uribe, Guillermo Velásquez, Francisco Javier Vélez   +9 more
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Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Crime and Punishment Analysis: Land Invasion "Para-institutions" in Cali

Ecos de Economía, 2014
Based on the crime economics of Becker (1968) and Ehrlich (1973), including the impact of the migratory flow, this paper studies the reasons why some individuals choose to strategically, rationally, and contingently become involved in illegal land ...
Enrique Javier Burbano Valencia
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