Results 31 to 40 of about 3,622,938 (386)

GPR162 activates STING dependent DNA damage pathway as a novel tumor suppressor and radiation sensitizer

open access: yesSignal Transduction and Targeted Therapy, 2023
In the treatment of most malignancies, radiotherapy plays a significant role. However, the resistance of cancer cells to ionizing radiation (IR) is the main reason for the failure of radiotherapy, which causes tumor recurrence and metastasis.
Yao Long   +14 more
doaj   +1 more source

The dark web trades wildlife, but mostly for use as drugs

open access: yesPeople and Nature, 2023
Contemporary wildlife trade is massively facilitated by the Internet. By design, the dark web is one layer of the Internet that is difficult to monitor and continues to lack thorough investigation.
Oliver C. Stringham   +14 more
doaj   +1 more source

Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis.

open access: yesGenes & Development, 2000
We have uncovered a novel functional relationship between the hyaluronan receptor CD44, the matrix metalloproteinase-9 (MMP-9) and the multifunctional cytokine TGF-beta in the control of tumor-associated tissue remodeling.
Q. Yu, I. Stamenkovic
semanticscholar   +1 more source

Simplified minimally invasive invasive parathyroidectomy [PDF]

open access: yesThe Annals of The Royal College of Surgeons of England, 2011
We agree with Wong et al that minimally invasive parathyroidectomy (MIP) is a safe and effective option in selected patients (approximately 50% of those with primary hyperparathyroidism) but would like to comment on some aspects of methodology and conclusions as reported in their case series. The authors quote a reference from 20031 to support their
Sabapathy P. Balasubramanian   +1 more
openaire   +3 more sources

Use of non-timber forest products from invasive alien Prosopis species (mesquite) and native trees in South Africa: implications for management

open access: yesForest Ecosystems, 2015
Background Prosopis species have been introduced to many areas outside their native range to provide benefits to local communities. Several Prosopis species and their hybrids (hereafter “mesquite”) have, however, become naturalised and invasive and now ...
Ross T Shackleton   +3 more
doaj   +1 more source

The invasion of circRNAs [PDF]

open access: yesRNA Biology, 2017
Single-stranded covalently closed circular RNA (circRNA) molecules come in many disguises, with different biogenesis mechanisms and functions.
Hansen, Thomas B., Kjems, Jørgen
openaire   +4 more sources

Invasive amphibians in southern Africa: A review of invasion pathways

open access: yesBothalia: African Biodiversity & Conservation, 2017
Background: Globally, invasive amphibians are known for their environmental and social impacts that range from poisoning of local fauna and human populations to direct predation on other amphibians.
John Measey   +5 more
doaj   +1 more source

Norepinephrine-stimulated HSCs secrete sFRP1 to promote HCC progression following chronic stress via augmentation of a Wnt16B/β-catenin positive feedback loop

open access: yesJournal of Experimental & Clinical Cancer Research, 2020
Background Sustained adrenergic signaling secondary to chronic stress promotes cancer progression; however, the underlying mechanisms for this phenomenon remain unclear.
Xia-Hui Lin   +9 more
doaj   +1 more source

CPT1A-mediated fatty acid oxidation promotes cell proliferation via nucleoside metabolism in nasopharyngeal carcinoma

open access: yesCell Death and Disease, 2022
As the first rate-limiting enzyme in fatty acid oxidation (FAO), CPT1 plays a significant role in metabolic adaptation in cancer pathogenesis. FAO provides an alternative energy supply for cancer cells and is required for cancer cell survival.
Min Tang   +22 more
doaj   +1 more source

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