Results 101 to 110 of about 6,389,024 (283)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Genomics reveals two distinct invasive lineages of Pereskia aculeata Miller in Australia: Implications for biological control

Biological Control
Understanding the invasion history of weeds can assist practitioners in making informed decisions about weed management. This information often plays a vital role in the selection of potential biological control (biocontrol) agents from the native range ...
Muhammad Nawaz, Andrew J. McConnachie, Graham A. McCulloch   +2 more
doaj   +1 more source

Introduced bullfrog facilitates pathogen invasion in the western United States.

PLoS ONE, 2018
Batrachochytrium dendrobatidis (Bd), a causal agent of the amphibian fungal skin disease chytridiomycosis, has been implicated in the decline and extinction of over 200 species worldwide since the 1970s.
Tiffany A Yap, Michelle S Koo, Richard F Ambrose, Vance T Vredenburg   +3 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Large-scale mitochondrial DNA analysis unravels the global invasion patterns of Pomacea snails (Gastropoda, Caenogastropoda, Ampullariidae) [PDF]

NeoBiota
Invasive apple snails (Pomacea spp.) have caused severe ecological and agricultural damage globally. Revealing their invasion history and genetic background is critical for effective management; however, traditional single-locus markers often provide ...
Jiale Fan, Yue Ma, Yanling Xia, Wencai Li, Chen Lin, Jun Liu, Yilei Zhao, Yuan Fu, Hui Liu, Diancheng Yang, Junchi Liu, Haimeng Li, Xiancui Lu, Tianming Lan   +13 more
doaj   +3 more sources

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Rewinding the invasion history of monk parakeets in Barcelona city: 1976-2022

Animal Biodiversity and Conservation
Rebobinando la invasión de las cotorras argentinas en la ciudad de Barcelona: 1976-2022 Predecir la abundancia y distribución futuras de especies exóticas introducidas es crucial para mitigar su impacto en los ecosistemas, pero es una tarea ardua.
N. A. Borray-Escalante, B. J. Hatchwell, L. Cardador, T. Montalvo, J. C. del Moral, B. Molina, J. G. Carrillo-Ortiz, J. Pascual, R. Rodriguez-Pastor, F. Uribe, L. Arroyo, J. Domènech, J. Clavell, D. Santos, X. Batllori, Z. Nuñez-Tobajas, J. C. Senar   +16 more
doaj   +1 more source

Growth of Invasive Lupinus polyphyllus (Fabaceae) is Not Affected by Site Invasion History

Annales Botanici Fennici, 2023
Kalske Aino, Ramula Satu
openaire   +2 more sources

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source