Results 51 to 60 of about 598 (250)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Lucentum, 1987 La ocultación monetal de La D'Eula (Crevillente, Alicante), contiene un conjunto de monedas datables entre los años 222 y 260, asociadas a algunos ejemplares más antiguos; las circunstancias del hallazgo y el análisis del mismo sugieren que el conjunto ...
Alfredo González Prats +1 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
El proceso histórico de las primitivas poblaciones peninsulares. II.
Zephyrus, 2009 Dos factores decisivos contribuyen a modelar el panorama cultural y étnico que nos ofrece la Península Ibérica en el primer milenio antes del o&imbio de Era.
Juan MALUQUER DE MOTES
doaj
Editorial: Carbon sequestration and climate change in crops, natural vegetation, and wetland dynamics in the high Andes. [PDF]
Front Plant Sci, 2023 Vento B, Cuesta F, Cavieres L.
europepmc +1 more source
Positive Interactions of Nonindigenous Species: Invasional Meltdown?
Biological Invasions, 1999 (Uploaded by Plazi for the IPBES Invasive Alien Species Assessment) Study of interactions between pairs or larger groups of nonindigenous species has been subordinated in the literature to study of interactions between nonindigenous and native species.
Simberloff, Daniel, Von Holle, Betsy
openaire +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Presencia de Chroanta ornatula (Herrich-Schaeffer) (Heteroptera: Pentatomidae) en Sudamérica
Revista Chilena de Entomología, 2019 Se presenta el primer registro en Sudamérica de la especie exótica invasora Chroanta ornatula (Herrich-Schaeffer, 1842) (Heteroptera: Pentatomidae), a partir de 63 ejemplares adultos capturados en la ciudad de Coro, región semiárida del Estado Falcón, al
Dalmiro Cazorla-Perfetti +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source