Results 91 to 100 of about 4,791,023 (305)

BraMARS: An Interpretable Histopathology‐Driven Deep Learning Model for Brain Metastasis Risk Stratification in Surgically Resected Limited‐Stage SCLC

Advanced Science, EarlyView.
This study presents BraMARS, an explainable deep learning model that estimates future brain metastasis risk in surgically resected limited‐stage small‐cell lung cancer using routine H&E‐stained whole‐slide images. By linking model‐attributed spatial histopathology with clinical outcomes and proteomic programs, BraMARS provides a biologically ...
Zijian Yang, Taolue Wang, Shilong Liu, Zicheng Zhang, Yibo Zhang, Fan Yang, Bo Yu, Shuaishuai Gao, Yu Chen, Lin Yang, Meng Zhou   +10 more
wiley   +1 more source

Effects of nano oxide particles on the growth and photosynthetic characteristics of okra plant under water deficiency

Folia Horticulturae
Drought, as abiotic stress, has significant detrimental effects on the growth, physiology, yield and nutritional quality of plants. The distinctive characteristics of nanoparticles (NPs) significantly contribute to essential physiological processes ...
Wang Jiyue, Xu Jiajun, Xie Rongrong, Chen Nian, Yang Mingli, Tian Xiaojian, Shi Denghong   +6 more
doaj   +1 more source

The distribution of range sizes of native and alien plants in four European countries and the effects of residence time [PDF]

, 2008
Aim Do the statistical distributions of range sizes of native and alien species differ? If so, is this because of residence time effects? And can such effects indicate an average time to a maximum?
Stout, J.C., Hill, M., Dehnen-Schmutz, Katharina, Kühn, I., Kühn, Ingolf, Klotz, Stefan, Stefan Klotz, Dehnen-Schmutz, K., Pyšek, P., Williamson, Mark, Ann Milbau, Petr Pyšek, Katharina Dehnen‐Schmutz, Williamson, M., Hill, Mark, Mark Williamson, Ingolf Kühn, Jane Stout, Mark Hill, Milbau, Ann, Klotz, S., Milbau , Ann, Stout, Jane, Pyšek, Petr   +23 more
core   +1 more source

A Small‐Molecule DEPTAC Rescues Cognitive Deficits by Targeted Dephosphorylation of Pathological Tau

Advanced Science, EarlyView.
TP2 is a fully synthetic small‐molecule dephosphorylation‐targeting chimera that recruits endogenous PP2A‐Bα to Tau, enabling targeted removal of pathological phosphate modifications. In two tauopathy mouse models, systemic TP2 reduces Tau pathology, preserves neuronal and synaptic integrity, improves neuroimmune homeostasis, and rescues cognition ...
Fei Sun, Yang Liu, Qiuzhi Zhou, Qingyuan Hu, Weixia Wang, Yue Xiao, Jingfen Su, Guanting Liu, Miaomiao Sun, Lixia Chen, Hua Li, Ying Yang, Jian‐Zhi Wang   +12 more
wiley   +1 more source

An Innervated Human Skin Equivalent that Electrically Encodes Mechanical and Thermal Stimuli

Advanced Science, EarlyView.
An innervated human skin equivalent is integrated with high‐density microelectrode arrays to reveal how engineered free nerve ending–like structures translate touch and temperature into electrical codes. Mechanical indentation and thermal stimulation engage the engineered somatosensory circuitry and evoke distinct firing and waveform signatures ...
Daniele Bellantoni, Costantino Casale, Marika Sperduti, Nevio L. Tagliamonte, Giorgia Imparato, Loredana Zollo, Paolo A. Netti   +6 more
wiley   +1 more source

Extraction and purification of total flavonoids from Zanthoxylum planispinum Var. Dintanensis leaves and effect of altitude on total flavonoids content

Scientific Reports
To investigate the impact of varying altitudes on the functional components of the leaves of Zanthoxylum planispinum var. Dintanensis, this research collected leaf samples from three different elevations: 610 m, 833 m, and 1083 m.
Jiyue Wang, Xianqi Huang, Zhenyu Chen, Nian Chen, Mingli Yang, Chenggang Liang, Yanghua Yu, Denghong Shi   +7 more
doaj   +1 more source

Comprehensive assessment of Erwinia amylovora: from establishment risk in global host production areas to dispersal dynamics and associated economic losses in China

Frontiers in Plant Science
Erwinia amylovora is the bacterial pathogen that causes fire blight and is considered one of the most important plant pathogenic bacteria in the world, posing a serious threat to pear and apple production. However, majority of the current risk assessment
Ming Li, Xiaoqing Xian, Zhenan Jin, Yuhan Qi, Jianyang Guo, Nianwan Yang, Nianwan Yang, Guifen Zhang, Jin Xu, Wanxue Liu   +9 more
doaj   +1 more source

Distribution Status for the Plants of Alien Species on the Baekdudaegan Protected Area, South Korea [PDF]

Geo Data
This study was conducted to provide information on alien species to the Baekdudaegan Protected Area eco-survey by Ministry of Environment in South Korea from 2015 to 2019. The scope of the survey is based on data from 26 subsections out of 44 subsections
Hyungsoo Seo, Hyun-Su Hwang, Hyun-Chul Shin, Daeun Kim, Donghui Choi, Youngjun Park   +5 more
doaj   +1 more source

Chemical Bond‐Orchestrated Energy Depletion to Augment Lung Cancer Chemo‐Immunotherapy

Advanced Science, EarlyView.
This study grafted dichloroacetic acid (DCA) into perylenediimide (PDI) skeleton via ionic or covalent bond to create novel metabolic agent PDIC‐AC and PDIC‐NAC, explicitly elaborated the underlying energy metabolism and therapeutic mechanism, and developed a promising strategy for energy metabolism‐targeting chemo‐immunotherapy by chemical bond ...
Xuejie Zhao, Yuting Liu, Xiao Huang, Liwen Zhao, Chunli Li, Yongwei Huang   +5 more
wiley   +1 more source

Effects of Microplastics and Cadmium on the Leptinotarsa decemlineata (Coleoptera: Chrysomelidae): An Evaluation Using a Two-Sex Life Table

Insects
This study utilized the age-stage, two-sex life table method to evaluate the toxic effects of polyethylene microplastics (PE, 300 mg/kg) and cadmium (Cd, 30 mg/kg), both individually and combined, on Leptinotarsa decemlineata.
Boling Liu, Yunhui Liu, Yi Zhang, Bingyu He, Yulin Gao, Chao Li   +5 more
doaj   +1 more source