Results 71 to 80 of about 4,791,023 (305)

TPI1 Loss Triggers a Metabolite‐Driven Mitochondrial Redox Vulnerability via the SARM1–cADPR–Ca2+ Axis

Advanced Science, EarlyView.
Metabolite‐driven redox stress governs cancer cell senescence. TPI1 deficiency elevates DHAP, initiating SARM1‐dependent cADPR‐Ca2+ release. Mitochondrial ROS surge subsequently induces DNA damage and senescence, offering a conserved therapeutic target in multiple cancers.
Chunyu Liu, Shun Wu, Chuang Wang, Zirui Zhou, Tianwei Cai, Wen Tao, Shidong Zuo, Chi Zhang, Yuhao Dong, Yi Feng, Qingbo Huang, Baojun Wang, Xin Ma, Haoli Ma, Xu Zhang, Yan Huang   +15 more
wiley   +1 more source

Potential distribution range of invasive plant species in Spain [PDF]

, 2012
Success of invasive species has been frequently estimated as the present distribution range size in the introduced region. However, the present distribution range is only a picture of the invasion for a given time step and do not inform on the potential ...
Gassó, Núria, Pino,Joan, Thuiller,Wilfried, Thuiller, Wilfried, Vilà, Montserrat, Vil\ue0, Montserrat, Gass\uf3, N\ufaria, Joan Pino, Gassó,Núria, Pino, Joan, Wilfried Thuiller, Núria Gassó, Montserrat Vilà, Vilà,Montserrat   +13 more
core   +1 more source

ZBTB11 Promotes Breast Cancer Progression by Activating FBXO28‐Mediated MST1 Degradation and Suppressing Hippo Signaling

Advanced Science, EarlyView.
ZBTB11 is identified as an oncogenic transcription factor that activates FBXO28 in breast cancer. FBXO28 promotes K48‐linked ubiquitination and degradation of MST1, suppressing Hippo signaling and enhancing epithelial–mesenchymal transition and metastasis. This transcription‐to‐ubiquitination cascade defines a prognostic biomarker axis and highlights a
An Xu, Xiang‐Nan Xu, Xiao Huang, Zhou Luo, Chun‐Lian Li, Yang Du, Cheng Yan, Xiao‐Jie Yu, Jian‐Wen Wang, Long‐Di Yao, De‐Yuan Fu   +10 more
wiley   +1 more source

Findings From the Pearl River Basin: Dissolved Oxygen Dominates Functional Trait Filtering and Diversity Patterns in Urban Rivers

Ecology and Evolution
Urbanization of river systems introduces novel environmental stressors—such as industrial pollutants and domestic wastewater—that impose selective pressures on aquatic species and reshape fish community structure.
Junhan Huang, Fandong Yu, Yuxiang Wang, Lu Shu, Miao Fang, Meng Xu, Xuejie Wang, Shiyu Jin, Si Luo, Dangen Gu   +9 more
doaj   +1 more source

Distribution and Ecological Risk of Ludwigia peploides in South Korea

Biology
The number of alien species introduced into South Korea continues to increase over the years. In particular, several plants have been introduced as ornamentals.
Aram Jo, Soo In Lee, Donghui Choi, Youngha Kim, Yong Ho Lee, Sun Hee Hong   +5 more
doaj   +1 more source

Welcome to InvasiveSpecies.gov!

, 2011
This website contains information about the purpose and work of the National Invasive Species Council, including its plans to prevent and manage invasive species, educational materials, budgetary and organizational documents of the Council, and other ...
National Invasive Species Council (U.S.)
core  

O‐GlcNAcylation Regulation of SNAP29‐Dependent Autophagy Activation Dictates Chemoresistance in Gastric Cancer

Advanced Science, EarlyView.
Model illustrating the proposed mechanism by which chemotherapy‐induced downregulation of OGT disrupts SNAP29 O‐GlcNAcylation, promoting STX17‐SNAP29‐VAMP8 SNARE complex assembly and protective autophagy, leading to chemoresistance, which in turn establishes a feedforward loop to perpetuate drug tolerance.
Liang Tang, Shaoji Zhao, Ziling Shao, Tao Luo, Baifu Peng, Yifan Liu, Jinning Ye, Jianjun Peng, Kaiyu Sun, Jianbo Xu   +9 more
wiley   +1 more source

Functional Characterization of Akt, a Serine/Threonine Kinase, in Tuta absoluta: A Key Regulator of Molting, Hormones, and Reproduction with Potential for RNAi Pest Control

Insects
Insect insulin signaling plays a central role in regulating development, metamorphosis, and reproduction, yet its mechanistic functions in the tomato leafminer, Tuta absoluta, a globally significant pest, remain poorly understood.
Chaoshan Liang, Jiahui Song, Kangkang Xu, Fanghao Wan, Guy Smagghe, Wenjia Yang   +5 more
doaj   +1 more source

Invasive species threats and opportunities: a primer for Oregon policymakers

, 2021
published by Oregon Invasive Species Council.Title from PDF cover (viewed on April 12, 2021).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

core  

Herbicide Metabolic Resistance in Poaceae Plants via the GA‐GID1/DELLA‐DOF2‐P450s Module

Advanced Science, EarlyView.
Plant hormone signaling modulates herbicide resistance in Echinochloa crus‐galli. The GA–DELLA–DOF2 cascade directly activates P450 detoxification genes in two Poaceae species, uncovering a core mechanism of metabolic herbicide resistance. ABSTRACT Barnyard grass (Echinochloa crus‐galli) is one of the world's most important weeds, and the evolution of ...
Junzhi Wang, Jiale Qi, Lin Wei, Qin Yu, Zhongyuan Liu, Lianyang Bai, Lang Pan   +6 more
wiley   +1 more source