Results 61 to 70 of about 9,953 (266)

Functional Characterization of Akt, a Serine/Threonine Kinase, in Tuta absoluta: A Key Regulator of Molting, Hormones, and Reproduction with Potential for RNAi Pest Control

Insects
Insect insulin signaling plays a central role in regulating development, metamorphosis, and reproduction, yet its mechanistic functions in the tomato leafminer, Tuta absoluta, a globally significant pest, remain poorly understood.
Chaoshan Liang, Jiahui Song, Kangkang Xu, Fanghao Wan, Guy Smagghe, Wenjia Yang   +5 more
doaj   +1 more source

Amassing Efforts against Alien Invasive Species in Europe

PLoS Biology, 2006
Almost daily, we can read newspaper articles voicing concerns about alien species and their impacts on native biodiversity, economic resources, and human health. Alien or non-native species introductions by humans rank as one of the two top factors (after habitat loss) leading to declines in biological diversity [1].
Shirley, Susan M., Kark, Salit
openaire   +7 more sources

Human Urine Stem Cells Alleviate Pulmonary Fibrosis via Inhibiting Macrophage‐Myofibroblast Transition

Advanced Science, EarlyView.
Therapeutic role and mechanism of human urine stem cells (hUSCs) in pulmonary fibrosis. hUSCs alleviated pulmonary fibrosis by selectively inhibiting macrophage‐myofibroblast transition (MMT) in two ways: on one hand, hUSCs inhibited mitochondrial reactive oxygen species (mtROS) production and apoptosis/senescence of epithelial cells in pulmonary ...
Zhou‐Hang Zhang, Guan‐Lin Guo, Xiao‐Hui Guan, Min Hu, Qi‐Ming Huang, Ding‐Wen Guo, Hao‐Cheng Gu, You‐Qiong Zhuo, Ning Li, Hong‐Bo Xin, Ke‐Yu Deng   +10 more
wiley   +1 more source

An inventory of invasive alien species in China

NeoBiota, 2012
(Uploaded by Plazi for the IPBES Invasive Alien Species Assessment) No abstract provided.
Xu, Haigen, Qiang, Sheng, Genovesi, Piero, Ding, Hui, Wu, Jun, Meng, Ling, Han, Zhengmin, Miao, Jinlai, Hu, Baishi, Guo, Jiangying, Sun, Hongying, Huang, Cheng, Lei, Juncheng, Le, Zhifang, Zhang, Xiaoping, He, Shunping, Wu, YU, Zheng, Zhou, Chen, Lian, Jarošik, Vojtěch, Pysek, Petr, Pysek, Petr   +21 more
openaire   +5 more sources

NIR‐II Light‐Triggered Electron Flow Initiates Cuproptosis‐Centered Thermoelectric‐Immunotherapy for Breast Cancer

Advanced Science, EarlyView.
A NIR‐II light‐activatable thermoelectric nanoreactor converts surface‐bound Cu2+ into bioactive Cu+ via directed electron flow. This spatiotemporally controlled reduction triggers potent cuproptosis and immunogenic cell death, eradicating primary tumors and, together with aPD‐1 therapy, suppressing metastases while establishing durable immune memory ...
Boyu Yuan, Qin Fan, Shushu Chu, Shining Yang, Yuechao Yang, Chenxi Zhang, Jinqiao Zhang, Xinran Qu, Yiju Wei, Xin Wang, Ziliang Dong   +10 more
wiley   +1 more source

Age-Stage, Two-Sex Life Table of Leptinotarsa decemlineata (Coleoptera: Chrysomelidae) Experiencing Cadmium Stress

Insects
Cadmium in agricultural soils has emerged as a substantial threat to crop health and yields through its bioaccumulation along the food chain, with further repercussions for the growth, development, and population dynamics of herbivorous insects.
Bingyu He, Jiebo Zhang, Yang Hu, Yi Zhang, Jianan Wang, Chao Li   +5 more
doaj   +1 more source

Identification of an Osteochondral Erosion Process in Gout Driven by Fibrinogen‐Integrin Activation and Local MSU Crystallization

Advanced Science, EarlyView.
Cartilage injury promotes local fibrinogen deposition, which accelerates monosodium urate crystallization and activates integrin‐mediated matrix‐degradation. This self‐amplifying cycle drives gout‐related cartilage erosion. Disrupting fibrinogen deposition or restoring the cartilage barrier could interrupt this vicious cycle.
Hanlin Xu, Simin Bi, Zhechen Liu, Xiaofeng Zhou, Hengwei Qin, Nicola Dalbeth, Minbiao Ji, Yinghui Hua   +7 more
wiley   +1 more source

TPI1 Loss Triggers a Metabolite‐Driven Mitochondrial Redox Vulnerability via the SARM1–cADPR–Ca2+ Axis

Advanced Science, EarlyView.
Metabolite‐driven redox stress governs cancer cell senescence. TPI1 deficiency elevates DHAP, initiating SARM1‐dependent cADPR‐Ca2+ release. Mitochondrial ROS surge subsequently induces DNA damage and senescence, offering a conserved therapeutic target in multiple cancers.
Chunyu Liu, Shun Wu, Chuang Wang, Zirui Zhou, Tianwei Cai, Wen Tao, Shidong Zuo, Chi Zhang, Yuhao Dong, Yi Feng, Qingbo Huang, Baojun Wang, Xin Ma, Haoli Ma, Xu Zhang, Yan Huang   +15 more
wiley   +1 more source

Effect of nanoparticles on the growth of okra cultivated in soil affected by rocky desertification

Scientific Reports
This study investigated the influence of various nanoparticles (NPs), including carbon-based NPs, Al2O3-NPs, SiO2-NPs, and TiO2-NPs, on the growth and physiology of okra plants cultivated in soil impacted by rocky desertification.
Jiyue Wang, Xiaojian Tian, Shuai Wei, Xiuhuan Meng, Nian Chen, Denghong Shi, Chenggang Liang   +6 more
doaj   +1 more source

ZBTB11 Promotes Breast Cancer Progression by Activating FBXO28‐Mediated MST1 Degradation and Suppressing Hippo Signaling

Advanced Science, EarlyView.
ZBTB11 is identified as an oncogenic transcription factor that activates FBXO28 in breast cancer. FBXO28 promotes K48‐linked ubiquitination and degradation of MST1, suppressing Hippo signaling and enhancing epithelial–mesenchymal transition and metastasis. This transcription‐to‐ubiquitination cascade defines a prognostic biomarker axis and highlights a
An Xu, Xiang‐Nan Xu, Xiao Huang, Zhou Luo, Chun‐Lian Li, Yang Du, Cheng Yan, Xiao‐Jie Yu, Jian‐Wen Wang, Long‐Di Yao, De‐Yuan Fu   +10 more
wiley   +1 more source