Results 61 to 70 of about 4,791,023 (305)

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source

Biological characterization and in vitro fungicide screening of a new causal agent of walnut leaf spot in Guizhou Province, China

Frontiers in Microbiology
Walnut (Juglans regia L.) is a widely grown nut plant worldwide, including in Guizhou Province, located in southwest China. The high quality and special taste make Guizhou walnuts, particularly those produced in Hezhang County, a “Chinese National ...
Xianxi Ao, Ting Shi, Wenjia Yang, Hao Ouyang, Ruidong Fan, Junaid Ali Siddiqui, Chaoming Wu, Zhoule Lv, Shasha Deng, Xiaoyulong Chen   +9 more
doaj   +1 more source

The Link Between Invasive Alien Species and Extinction [PDF]

Biosphere
Invasive alien species (IAS) can cause the extinction of a taxon. However, debate continues over the significance of IAS as drivers of extinction globally, the level of threat they pose to endangered species, and whether conservation efforts against IAS should take priority over other factors, such as habitat loss or climate change.
Kelvin S.-H. Peh, Zoe Bird
openaire   +1 more source

The EU phytosanitary system and the CBD guiding principles on invasive alien species

, 2005
The phytosanitary provisions and systems of the European Union (EU) and its member states have been fully harmonized since 1993. They are in place to minimize the introduction of alien organisms that are harmful to plants and plant products and to limit ...
Unger, Jens-Georg
core  

NIR‐II Light‐Triggered Electron Flow Initiates Cuproptosis‐Centered Thermoelectric‐Immunotherapy for Breast Cancer

Advanced Science, EarlyView.
A NIR‐II light‐activatable thermoelectric nanoreactor converts surface‐bound Cu2+ into bioactive Cu+ via directed electron flow. This spatiotemporally controlled reduction triggers potent cuproptosis and immunogenic cell death, eradicating primary tumors and, together with aPD‐1 therapy, suppressing metastases while establishing durable immune memory ...
Boyu Yuan, Qin Fan, Shushu Chu, Shining Yang, Yuechao Yang, Chenxi Zhang, Jinqiao Zhang, Xinran Qu, Yiju Wei, Xin Wang, Ziliang Dong   +10 more
wiley   +1 more source

Invasive Species Definition Clarification and Guidance White Paper

, 2006
Paper discussing a "a non-regulatory policy interpretation of the term invasive species" through a positional defintion of what and what does not constittue an invasive species along with examples of impacts caused by invasive species.
Definitions Subcommittee of the Invasive Species Adivsory Committee
core  

IPBES Invasive alien species assessment, data management report for Chapter 3. Section: Research

, 2021
Section 3.2.4.1 assesses the role of the activities, facilities and devices used in Scientific Research as drivers of transportation, introduction, establishment and spread of invasive alien species, including research on alien species for chapter 3 of ...
IPBES technical support unit for the assessment of invasive alien species
core   +1 more source

Identification of an Osteochondral Erosion Process in Gout Driven by Fibrinogen‐Integrin Activation and Local MSU Crystallization

Advanced Science, EarlyView.
Cartilage injury promotes local fibrinogen deposition, which accelerates monosodium urate crystallization and activates integrin‐mediated matrix‐degradation. This self‐amplifying cycle drives gout‐related cartilage erosion. Disrupting fibrinogen deposition or restoring the cartilage barrier could interrupt this vicious cycle.
Hanlin Xu, Simin Bi, Zhechen Liu, Xiaofeng Zhou, Hengwei Qin, Nicola Dalbeth, Minbiao Ji, Yinghui Hua   +7 more
wiley   +1 more source

Identification and Functional Characterization of Nine Glutathione S-Transferase Genes in Lasioderma serricorne Reveals Their Roles in Detoxification of Emerging Fumigants

Agriculture
The cigarette beetle, Lasioderma serricorne, is a globally important pest of stored products, and prolonged fumigant use has accelerated resistance development. Glutathione S-transferases (GSTs) are key phase II detoxification enzymes that mediate insect
Mingxun Zu, Yu Shen, Kangkang Xu, Qian Guo, Wenjia Yang, Guy Smagghe, Can Li   +6 more
doaj   +1 more source

IPBES Invasive alien species assessment, data management report for Chapter 3. Section: Urbanisation and pollution

, 2021
Section 3.4.6 assesses the interaction between urbanisation and pollution as a driver for the introduction of invasive alien species in Chapter 3 of IPBES thematic assessment of invasive alien species and their control. The experts conducted a systematic
IPBES technical support unit for the assessment of invasive alien species
core   +1 more source