Results 61 to 70 of about 126,827 (286)

The MMP‐9/TIMP‐1 Ratio and Concentrations of Osteopontin Are Elevated in Cerebrospinal Fluid of People With Multiple Sclerosis and Decrease After Autologous Hematopoietic Stem Cell Transplantation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the utility of cerebrospinal fluid (CSF) biomarkers—matrix metalloproteinase‐9 (MMP‐9), tissue inhibitor of metalloproteinases‐1 (TIMP‐1), the MMP‐9/TIMP‐1 ratio, and osteopontin (OPN)—as indicators of blood–brain barrier (BBB) integrity and disease activity in people with relapsing–remitting multiple sclerosis (pwMS ...
Ivan Pavlovic, Ida Erngren, Kim Kultima, Anders Larsson, Malin Müller, Anna Wiberg, Joachim Burman   +6 more
wiley   +1 more source

Diagnosis and management of invasive fungal diseases in non-neutropenic ICU patients, with focus on candidiasis and aspergillosis: a comprehensive review

Frontiers in Cellular and Infection Microbiology
Invasive fungal diseases pose a significant threat to non-neutropenic ICU patients, with Candida and Aspergillus infections being the most common. However, diagnosing these infections in the ICU population remains challenging due to overlapping clinical ...
Afzal Azim, Armin Ahmed
doaj   +1 more source

Presentation of Invasive Fungal Rhinosinusitis in Sudanese Children: A Report of Four Cases

Sudan Journal of Medical Sciences, 2018
Fungal rhinosinusitis (FS) is considered as a disease spectrum that ranges from allergic fungal sinusitis (AFS) and chronic fungal rhinosinusitis (CFS) to invasive fungal rhinosinusitis (IFS) invading the orbit, Dura, and intra-cranium.
Sharfi Ahmed, Khalid Awad Elseed
doaj   +1 more source

Voriconazole for secondary prophylaxis of invasive fungal infections in allogeneic stem cell transplant recipients: results of the VOSIFI study

Haematologica, 2010
Background Recurrence of prior invasive fungal infection (relapse rate of 30–50%) limits the success of stem cell transplantation. Secondary prophylaxis could reduce disease burden and improve survival.Design and Methods A prospective, open-label ...
Catherine Cordonnier, Montserrat Rovira, Johan Maertens, Eduardo Olavarria, Catherine Faucher, Karin Bilger, Arnaud Pigneux, Oliver A Cornely, Andrew J. Ullmann, Rodrigo Martino Bofarull, Rafael de la Cámara, Maja Weisser, Effie Liakopoulou, Manuel Abecasis, Claus Peter Heussel, Marc Pineau, Per Ljungman, Hermann Einsele   +17 more
doaj   +1 more source

Acute invasive fungal rhinosinusitis in pediatric patients with oncohematological diseases

Hematology, Transfusion and Cell Therapy, 2022
Introduction: Invasive fungal diseases represent important causes of morbidity and mortality among pediatric oncohematological patients. Acute invasive fungal rhinosinusitis is a rare and aggressive disease that occurs mainly in immunocompromised ...
Lorrane Caroline Braga Rodrigues, Alessandro Fernandes Guimaraes, Isamara Simas de Oliveira, Pedro Henrique Medici de Sousa, Roberta Maia de Castro Romanelli, Fabiana Maria Kakehasi, Karla Emília de Sá Rodrigues   +6 more
doaj   +1 more source

An evolutionary perspective on zinc uptake by human fungal pathogens [PDF]

, 2015
DW is supported by a Sir Henry Dale Fellowship jointly funded by the Wellcome Trust and the Royal Society (Grant Number 102549/Z/13/Z).Peer reviewedPublisher ...
Wilson, Duncan
core   +1 more source

Acute invasive fungal rhinosinusitis with disseminated fusariosis mimicking chicken pox in an immunocompromised child

Pediatria i Medycyna Rodzinna, 2019
Acute invasive fungal rhinosinusitis is a rare sinonasal infection. It usually occurs in immunocompromised patients. The presentation of acute invasive fungal rhinosinusitis with disseminated fusariosis mimicking varicella zoster cutaneous lesion is ...
Farah Dayana Zahedi, Lian See Sandie Ewe, Salina Husain, Kwee Chu Keah   +3 more
doaj   +1 more source

Allergic bronchopulmonary aspergillosis: diagnostic and treatment challenges [PDF]

, 2016
Allergic bronchopulmonary aspergillosis (ABPA) is a pulmonary disorder, occurring mostly in asthmatic and cystic fibrosis patients, caused by an abnormal T-helper 2 lymphocyte response of the host to Aspergillus fumigatus antigens.
CINICOLA, BIANCA LAURA, DUSE, MARZIA, Laitano, Rossella, LEONARDI, LUCIA   +3 more
core   +1 more source

Host‐Directed Biomaterials for Combatting Bloodstream Infections: From Macrocyclic Peptides to Immune‐Activating Cell Backpacks

Advanced Functional Materials, EarlyView.
Bloodstream infections (BSI) are one of the leading causes of mortality and morbidity in both civilian and military populations. This paper summarizes recent progress in novel treatment strategies to manage BSI arising from both bacterial and fungal pathogens using molecules, particles, and materials to elicit host‐directed immunity.
Thomas Thomou, Jagadish Krishnappa, Justin B. Schaal, Prasad Tongaonkar, Dat Q. Tran, Wenchao Gu, Yung‐Fu Chang, Michael E. Selsted, Shaoyi Jiang, Samir Mitragotri, Michael Super, Christopher J. Bettinger   +11 more
wiley   +1 more source

Prediction of invasion from the early stage of an epidemic [PDF]

, 2012
Predictability of undesired events is a question of great interest in many scientific disciplines including seismology, economy, and epidemiology. Here, we focus on the predictability of invasion of a broad class of epidemics caused by diseases that lead
Gilligan, Christopher A., Neri, Franco M., Perez-Reche, Francisco J., Taraskin, Sergei N.   +3 more
core   +2 more sources