Results 51 to 60 of about 122,887 (285)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Voriconazole for secondary prophylaxis of invasive fungal infections in allogeneic stem cell transplant recipients: results of the VOSIFI study

Haematologica, 2010
Background Recurrence of prior invasive fungal infection (relapse rate of 30–50%) limits the success of stem cell transplantation. Secondary prophylaxis could reduce disease burden and improve survival.Design and Methods A prospective, open-label ...
Catherine Cordonnier, Montserrat Rovira, Johan Maertens, Eduardo Olavarria, Catherine Faucher, Karin Bilger, Arnaud Pigneux, Oliver A Cornely, Andrew J. Ullmann, Rodrigo Martino Bofarull, Rafael de la Cámara, Maja Weisser, Effie Liakopoulou, Manuel Abecasis, Claus Peter Heussel, Marc Pineau, Per Ljungman, Hermann Einsele   +17 more
doaj   +1 more source

Adherence to recommendations for the evaluation and management of fungal infections in a referral teaching hospital in Iran: A retrospective cross-sectional study

Journal of Infection in Developing Countries, 2023
Introduction: Early diagnosis and appropriate management of fungal infections are critical for reducing complications and mortality in hospitalized patients.
Haura Atashgar, Hossein Khalili, Mohammadreza Salehi, Mostafa Mohammadi   +3 more
doaj   +1 more source

Candida auris, what do paediatricians need to know? [PDF]

, 2018
AW is supported by the Wellcome Trust Strategic Award (grant 097377) and the MRC Centre for Medical Mycology (grant MR/N006364/1) at the University of Aberdeen.Peer reviewedPublisher ...
Warris, Adilia
core   +1 more source

Vaccines for invasive fungal infections [PDF]

F1000 Medicine Reports, 2011
(Uploaded by Plazi for the Bat Literature Project) Morbidity and mortality from invasive fungal infections remain unacceptably high despite availability of new antifungal agents, underscoring the need for more effective preventative strategies. Due to our enhanced understanding of the host defense and pathogenetic mechanisms that lead to invasive ...
openaire   +2 more sources

Difficult diagnosis of invasive fungal infection predominantly involving the lower gastrointestinal tract in acute lymphoblastic leukaemia

Medical Mycology Case Reports, 2016
Invasive fungal infections are most commonly seen in immunocompromised patients and usually affect the respiratory system. Gastrointestinal system involvement of mucormycosis and invasive aspergillosis is rarely reported in childhood.
Gulhadiye Avcu, Deniz Yilmaz Karapinar, Pinar Yazici, Muhterem Duyu, Suleyha Hilmioglu Polat, Berna Atabay, Basak Doganavsargil, Bulent Karapinar   +7 more
doaj   +1 more source

Posaconazole and fluconazole prophylaxis during induction therapy for pediatric acute lymphoblastic leukemia

Journal of Microbiology, Immunology and Infection, 2021
Purpose: To assess and compare the efficacy and safety of posaconazole with fluconazole for the prevention of invasive fungal infections in children who were undergoing induction therapy for acute lymphoblastic leukemia (ALL).
Tian Zhang, Jie Bai, Mingxia Huang, Ruixiao Li, Yang Liu, Ansheng Liu, Jixin Liu   +6 more
doaj   +1 more source

Host‐Directed Biomaterials for Combatting Bloodstream Infections: From Macrocyclic Peptides to Immune‐Activating Cell Backpacks

Advanced Functional Materials, EarlyView.
Bloodstream infections (BSI) are one of the leading causes of mortality and morbidity in both civilian and military populations. This paper summarizes recent progress in novel treatment strategies to manage BSI arising from both bacterial and fungal pathogens using molecules, particles, and materials to elicit host‐directed immunity.
Thomas Thomou, Jagadish Krishnappa, Justin B. Schaal, Prasad Tongaonkar, Dat Q. Tran, Wenchao Gu, Yung‐Fu Chang, Michael E. Selsted, Shaoyi Jiang, Samir Mitragotri, Michael Super, Christopher J. Bettinger   +11 more
wiley   +1 more source

Value of platelet count in the early diagnosis of nosocomial invasive fungal infections in premature infants

Platelets, 2018
The aim of this study was to investigate the value of a platelet count (PLT) in the early diagnosis of nosocomial invasive fungal infections in premature infants.
Yu-Chen Yang, Jian Mao
doaj   +1 more source

Near-fatal mucormycosis post-double lung transplant presenting as uncontrolled upper gastrointestinal haemorrhage

Medical Mycology Case Reports, 2018
Invasive fungal infections in immunosuppressed transplant patients are associated with significant morbidity and mortality. We present a case of splenic mucormycosis post-double lung transplant, presenting as uncontrolled near-fatal upper ...
Ciara O’Connor, Ciaran Farrell, Aurelie Fabre, Donna Eaton, Karen Redmond, David G. McSharry, John B. Conneely, Conor J. Shields, Jim J. Egan, Margaret M. Hannan   +9 more
doaj   +1 more source