Results 71 to 80 of about 2,457,946 (249)

Diagnosis and management of invasive fungal diseases in non-neutropenic ICU patients, with focus on candidiasis and aspergillosis: a comprehensive review

Frontiers in Cellular and Infection Microbiology
Invasive fungal diseases pose a significant threat to non-neutropenic ICU patients, with Candida and Aspergillus infections being the most common. However, diagnosing these infections in the ICU population remains challenging due to overlapping clinical ...
Afzal Azim, Armin Ahmed
doaj   +1 more source

Posaconazole and fluconazole prophylaxis during induction therapy for pediatric acute lymphoblastic leukemia

Journal of Microbiology, Immunology and Infection, 2021
Purpose: To assess and compare the efficacy and safety of posaconazole with fluconazole for the prevention of invasive fungal infections in children who were undergoing induction therapy for acute lymphoblastic leukemia (ALL).
Tian Zhang, Jie Bai, Mingxia Huang, Ruixiao Li, Yang Liu, Ansheng Liu, Jixin Liu   +6 more
doaj   +1 more source

Polymorphisms in tumor necrosis factor-α increase susceptibility to intra-abdominal Candida infection in high-risk surgical ICU patients*

, 2014
To evaluate the influence of genetic polymorphisms on the susceptibility to Candida colonization and intra-abdominal candidiasis, a blood culture-negative life-threatening infection in high-risk surgical ICU patients.; Prospective observational cohort ...
Flueckiger, Ursula Maria, Marchetti, O., Fungal Infection Network of Switzerland,, Orasch, C., Flueckiger, U.M., Orasch, Christina, Marchetti, Oscar, Wójtowicz, A., Calandra, T., Lamoth, Frederic, Bochud, P.Y., Bille, Jacques, Fungal Infection Network of, Switzerland, Wójtowicz, Agnieszka, Siegemund, M., Zimmerli, S., Bille, J., Lamoth, F., Eggimann, Philippe, Calandra, Thierry, Tissot, F., Bochud, Pierre-Yves, Zimmerli, Stephan, Tissot, Frederic, Eggimann, P., Siegemund, Martin   +25 more
core   +1 more source

Synergy in efficacy of fungal entomopathogens and permethrin against West African insecticide-resistant Anopheles gambiae mosquitoes. [PDF]

, 2010
BACKGROUND: Increasing incidences of insecticide resistance in malaria vectors are threatening the sustainable use of contemporary chemical vector control measures.
Knols, B.G.J., Mark Rowland, Annabel F V Howard, Farenhorst, Marit, Knols, Bart G. J., N’Guessan Raphael, N'Guessan, R., Howard, A.F.V., Thomas, Matthew B., Annabel F. V. Howard, Rowland Mark, Knols, Bart GJ, Farenhorst, M., N'Guessan, Raphael, Takken, W., Thomas Matthew B., Raphael N’Guessan, Farenhorst Marit, Howard Annabel F. V., Rowland, Mark, Howard, Annabel F. V., Matthew B. Thomas, Thomas, Matthew B, Howard, Annabel FV, Takken, Willem, Takken Willem, Knols Bart G. J., Thomas, M.B., Matthew B Thomas, Rowland, M., Raphael N'Guessan, Marit Farenhorst, Bart G. J. Knols, Bart G J Knols, Willem Takken   +34 more
core   +3 more sources

Herbivory‐Induced Stomatal Opening Triggers the Dispersal of an Invasive Insect Herbivore

Advanced Science, EarlyView.
The invasive leafminer Phthorimaea absoluta uniquely manipulates plant defenses by inducing stomatal opening in tomato. This response, mediated by the stomatal regulator IQM1, enhances the release of the repellent volatile benzaldehyde. This volatile triggers the dispersal of adult moths, facilitates colonization of new hosts, and leads to rapid ...
Limin Chen, Xiaowei Li, Yaru Wang, Farman Ullah, Shuxing Zhou, Lemeng Dong, Weizhong He, Harro J. Bouwmeester, Youming Hou, Ian T. Baldwin, Yaobin Lu   +10 more
wiley   +1 more source

A Synthetic β‐Mannan Epitope Enables Immunization and Detection of Candida auris

Angewandte Chemie, EarlyView.
A synthetic β‐mannan epitope enables both active and passive immunization against Candida auris. Conjugation to the carrier protein CRM197 induces protective antibody responses, while monoclonal antibodies targeting the same epitope support detection using a lateral flow assay, linking glycochemistry with antifungal prevention and diagnostics ...
Emelie E. Reuber, Arnab Pradhan, Ian Leaves, Rajat K. Singh, Emer Hickey, Carola Geiler, Neil A. R. Gow, Alistair J. P. Brown, Peter H. Seeberger   +8 more
wiley   +2 more sources

The Mitogen‐Activated Protein Kinase GhNTF3 Modulates the Arbuscular Mycorrhizal Symbiosis‐Immunity Trade‐Off in Cotton by Regulating Salicylic Acid Biosynthesis

Advanced Science, EarlyView.
AM symbiosis induces GhWAK13 to promote fungal colonization. GhNTF3 negatively regulates symbiosis by promoting SA biosynthesis. GhWAK13 sequesters GhNTF3 at the membrane, limiting its nuclear translocation and relieving SA‐mediated suppression. Under Verticillium stress, GhNTF3 enters the nucleus and interacts with GhJAZ6 to activate SA signaling ...
Shuangjie Jia, Jingshang Wen, Jihang Li, Meina Feng, Yiming He, Ruojun Liu, Qian Liu, Junli Zhang, Kai Cheng, Xiangyu Zhang, Xiao Zhang   +10 more
wiley   +1 more source

Invasive fungal infections in liver diseases

Hepatology Communications, 2023
Patients with liver diseases, including decompensated cirrhosis, alcohol-associated hepatitis, and liver transplant recipients are at increased risk of acquiring invasive fungal infections (IFIs). These infections carry high morbidity and mortality.
Barros, Nicolas, Rosenblatt, Russell E., Phipps, Meaghan M., Fomin, Vladislav, Mansour, Michael K.   +4 more
openaire   +3 more sources

Intensive care unit-related fluconazole use in Spain and Germany: patient characteristics and outcomes of a prospective multicenter longitudinal observational study [PDF]

, 2013
Background: Candida spp. are a frequent cause of nosocomial bloodstream infections worldwide. Objective: To evaluate the use patterns and outcomes associated with intravenous (IV) fluconazole therapy in intensive care units in Spain and Germany ...
Wissing, Heimo, Nocea, Gonzalo, Krobot, Karl J., Kaskel, Peter, Ballus, Jose, Bingold, Tobias Michael, Kumar, Ritesh N., Mavros, Panagiotis   +7 more
core   +1 more source

Repurposing FDA‐Approved Drugs to Inhibit Fungal PPTases for Broad‐Spectrum Synergy

Advanced Science, EarlyView.
Fungal secondary metabolites serve as crucial virulence effectors; however, the potential of their biosynthetic pathways as antifungal targets remains inadequately comprehended. Repurposed FDA‐approved drugs inhibit fungal PPTase (essential for secondary metabolism) in vivo.
Zili Song, Can Zhao, Qiaoling Wang, Hongjiao Zhang, Xiao Liu, Linqi Wang, Michael Bromley, Wen‐Bing Yin   +7 more
wiley   +1 more source