Results 81 to 90 of about 2,457,946 (249)

Symbiont‐Induced HSP83 Establishes Two‐Tiered Control of Antifungal Immunity in an Invasive Beetle–Fungus Complex

Advanced Science, EarlyView.
In an invasive beetle–fungus complex, the mutualist Leptographium procerum induces host HSP83 and modulates Toll‐dependent antifungal immunity. HSP83 mediates two‐tiered control by associating with selected fungal recognition receptors and restraining Dorsal‐driven antimicrobial peptide transcription.
Qingtai Yang, Zhudong Liu, Yuqiao Yin, Jing Su, Dunyang Yu, Longsheng Xing, Zhen Zou, Le Kang, Jianghua Sun   +8 more
wiley   +1 more source

Invasive Fungal Infections [PDF]

, 2018
Invasive fungal diseases (IFD) are frequent infectious complications of HSCT. The 12 m cumulative incidence approaches 8–10% in URD or mismatched allo-HSCT, 6% in MRD allo-HSCT, and less than 2% following auto-HSCT (Kontoyiannis et al. 2010). However, higher incidences (up to 17%) have been reported in haplo-identical HSCT and CBT.
openaire   +2 more sources

Identification of Different Fungal Infections in Intensive Care Units in Al-Zahraa University Hospital [PDF]

Al-Azhar International Medical Journal, 2000
Background: Invasive fungal infections are frequent and associated with morbidity and mortality in critically ill patients. Early recognition, diagnosis, and treatment decrease the magnitude of fungal infections.
Esraa Elfiqy, Emtethal El Kholy, Marwa El Said   +2 more
doaj   +1 more source

Invasive fungal infections in transplant recipients [PDF]

Therapeutic Advances in Infectious Disease, 2013
Invasive fungal infections are an important cause of morbidity and mortality in hematopoietic stem cell transplant and solid organ transplant recipients. Evolving transplant modalities and techniques, complex and extensive immunosuppressant strategies, and the increased use of broad spectrum antifungal prophylaxis has greatly impacted the epidemiology ...
Jose A, Vazquez, Marisa H, Miceli, George, Alangaden   +2 more
openaire   +2 more sources

Host genotype shapes the foliar fungal microbiome of balsam poplar (Populus balsamifera) [PDF]

, 2013
Foliar fungal communities of plants are diverse and ubiquitous. In grasses endophytes may increase host fitness; in trees, their ecological roles are poorly understood.
Fankhauser, Johnathon D., Johnathon D Fankhauser, Johnathon D. Fankhauser (104143), Matthew S Olson, Miklós Bálint (104125), Schmitt, Imke, Olson, Matthew S., Imke Schmitt (104151), Tiffin, Peter, Meike Piepenbring, Hallström, Björn, Matthew S. Olson (104138), Peter Tiffin, Robert B. O’Hara (104134), Peter Tiffin (104127), Björn Hallström (104129), Bálint, Miklós, Imke Schmitt, Miklós Bálint, Robert B O'Hara, O'Hara, Robert B., Piepenbring, Meike, Björn Hallström, Meike Piepenbring (104147)   +23 more
core   +1 more source

Leveraging Microphysiological Systems to Facilitate Neutrophil‐Based Cancer Immunotherapy

Advanced Science, EarlyView.
Microphysiological systems are emerging as powerful human‐relevant platforms for studying neutrophil biology in cancer. Current applications of spheroids, organoids, and organ‐on‐a‐chip models are reviewed, together with future opportunities in behaviorome profiling, multi‐omics integration, personalized medicine, immune crosstalk, and multi‐organ ...
Shuai Shao, Markus Isfeld Diehl, Caroline N. Jones   +2 more
wiley   +1 more source

Pathological Signal‐Responsive Nanoplatforms for Sepsis: Integrating Biomarker Sensing With Spatiotemporal Drug Delivery and Immunomodulation

Advanced Science, EarlyView.
Biomarker‐triggered nanoplatforms transform sepsis therapy by coupling pathological sensing with precision drug release. This review reveals how microenvironment‐responsive nanomedicines enable stage‐specific intervention, improve therapeutic efficacy, and minimize systemic toxicity, while highlighting emerging opportunities for AI‐assisted and ...
Yukun Liu, Kang Wang, Kwet Kyawl Yan, Zhikai Xu, Xuan Zhao, Xiangjun Bai, Zhanfei Li, Yuchang Wang   +7 more
wiley   +1 more source

Modes of action of the new arylguanidine abafungin beyond interference with ergosterol biosynthesis and in vitro activity against medically important fungi [PDF]

, 2008
Background: In contrast to the increasing numbers of agents for the treatment of invasive fungal infections, discoveries of new antifungal agents with therapeutic value in dermatomycoses are reported only rarely.
Borelli, Claudia, Korting, Hans Christian, Tietjen, K., Niewerth, M., Schaller, M., Lang-Fugmann, S., Tiemann, R., Fugmann, B., Baasner, B., Nocker, K., Berg, D.   +10 more
core   +1 more source

Molecular Bases and Genetic Design of Rice Disease Resistance for Optimized Yield and Sustainable Agriculture

Advanced Science, EarlyView.
This study integrates rice immune perception, signal transduction, and resistance output into a multi‐omics framework. By combining high‐throughput sequencing, phenomics, and AI‐assisted design with marker‐assisted selection, gene editing, and rapid domestication, we aim to accelerate the precise breeding of disease‐resistant rice varieties by ...
Xinyue Hou, Yuanjiang Cui, Chaoqing Ding, Qian Qian, Deyong Ren   +4 more
wiley   +1 more source

ROUTINARY FLUCONAZOLE PROPHYLAXIS IN VLBW NEONATES: IS A RIGHT CHOISE? [PDF]

Euromediterranean Biomedical Journal, 2016
This is a retrospective cohort study with the aim of evaluating fluconazole efficacy in preventing invasive fungal infections in very low birth weight newborns, in our NICU setting. Neonates weighing less than 1500g at birth, born between January 2013
Antonio Di Mauro
doaj   +1 more source