Results 221 to 230 of about 1,781,803 (291)

Feasibility and Safety of Venetoclax for Cytoreduction During Induction Therapy in Newly Diagnosed Acute Promyelocytic Leukemia

European Journal of Haematology, EarlyView.
ABSTRACT Objective This study aimed to evaluate the feasibility and safety of venetoclax as a cytoreductive strategy during induction therapy in newly diagnosed acute promyelocytic leukemia (APL), and to provide an exploratory description of its early efficacy.
Yu Wang, Rong Xiao, Xiaobing Huang, Yi Xiao   +3 more
wiley   +1 more source

Voriconazole as a Secondary Prophylaxis for Invasive Fungal Infections in Allogeneic Hematopoietic Stem Cell Transplantation: Real-world Evidence From a Major Transplantation Center in Taiwan. [PDF]

Open Forum Infect Dis
Wang YW, Cheng CN, Lin CT, Tsai XC, Huang JD, Hsieh ZD, Liao XW, Lin FJ, Chen YC, Kuo CH, Wu SJ, Lin SW.   +11 more
europepmc   +1 more source

Pronounced Reductions in Plasma Citrulline Indicate Severe Intestinal Mucosal Barrier Injury During Induction Therapy for Pediatric Acute Myeloid Leukemia

European Journal of Haematology, EarlyView.
ABSTRACT Objectives Pediatric acute myeloid leukemia (AML) chemotherapy regimens are frequently burdened by fever episodes, systemic inflammation and bloodstream infections (BSI). Mucosal barrier injury may contribute to these complications, but its role in childhood AML remains uninvestigated.
Carla Warley Kjær, Maria Ebbesen Sørum, Silvia De Pietri, Claus Moser, Malene Johanne Petersen, Marianne Hoffmann, Henrik Hasle, Sarah Weischendorff, Klaus Müller   +8 more
wiley   +1 more source

Factors associated with beyond-therapeutic serum voriconazole trough level among critically ill patients with invasive fungal infections. [PDF]

BMC Infect Dis
Lee YC, Ku WC, Hung YL, Chen YC, Hung CF, Wang JT, Liu WL.   +6 more
europepmc   +1 more source

Transgenic selection and underlying mechanisms in apicomplexan parasites

The FEBS Journal, EarlyView.
Transgenic selection markers have driven genetic engineering in apicomplexans, enabling precise, iterative experiments. This review discusses mechanistic details of drug selection markers, strategies for marker recycling, and practical considerations for several clinically relevant parasites.
Swaroop Peddiraju, Rakhee Lohia, Nishith Gupta   +2 more
wiley   +1 more source

Insights into tandem dioxygenases—copper radical oxidases in fungal Phytopathogens of the Colletotrichum acutatum species complex

The FEBS Journal, EarlyView.
In Colletotrichum acutatum species complex, conserved ring‐cleavage dioxygenases located adjacent to AA5_2 enzymes were investigated as potential redox partners. Biochemical analyses identified the dioxygenases as intradiol‐cleaving enzymes preferentially oxidizing methyl‐substituted catechols, while AA5_2 enzymes displayed weak alcohol oxidase ...
Radka Končitíková, David Ribeaucourt, Mireille Haon, David Navarro, Elodie Drula, Bastien Bissaro, Jean‐Guy Berrin, Mickael Lafond   +7 more
wiley   +1 more source

Invasive Fungal Infections in Orthotopic Heart Transplant Patients: Incidence and Risk Factors in the Modern Era. [PDF]

Clin Transplant
Hasan L, Thirunavukarasu Murugan L, Hsich E, Tong MZ, Brizendine KD.   +4 more
europepmc   +1 more source

A longitudinal study of avian pox in a small passerine, the Dunnock (Prunella modularis)

Ibis, EarlyView.
Long‐term, longitudinal studies of disease in wild bird populations are rare. Diseases are important determinants of bird survival and may spill‐over into other species including livestock and, in some cases, humans. Avian pox is a globally distributed disease, resulting from infection by viruses in the genus Avipoxvirus (APV).
Denise C. Wawman, Steven R. Fiddaman, Becki Lawson, Maria D. Christodoulou, Ben C. Sheldon, Adrian L. Smith   +5 more
wiley   +1 more source

Epidemiology and clinical characterization of invasive fungal infections in pediatric hemato-oncologic patients at a tertiary referral center in Northeastern Mexico. [PDF]

Ann Hematol
Vaquera-Aparicio DN, Castillo-Bejarano JI, Mascareñas-de-Los-Santos AH, Treviño RJ, Arcos-Viscarra PS, Morales-López ML, Guerrero-Delgado AS.   +6 more
europepmc   +1 more source

Species diversity and host plant associations of ambrosia beetles in Southeast Asian forests of Laos and Vietnam revealed by DNA barcoding

Insect Conservation and Diversity, EarlyView.
Integrative DNA barcoding of ambrosia beetles and host plants revealed 27 beetle species across 16 genera and extensive, previously undocumented host plant diversity in Laos and Vietnam. Host specificity varied widely among ambrosia beetles, with Xylosandrus crassiusculus emerging as a dominant generalist associated with 19 host species from 12 plant ...
Bounsanong Chouangthavy, Phongphayboun Phonepaseuth, Emiko Oguri, Shuichiro Tagane, Phetlasy Souladeth, Phonepadith Phewphanh, Dac Dai Nguyen, Anh D. Nguyen, Noriaki Murakami, Katsuyuki Eguchi, Takahiro Yoshida   +10 more
wiley   +1 more source