MET∆14 promotes a ligand-dependent, AKT-driven invasive growth [PDF]
Life Science Alliance, 2022 The MET oncogene’s most frequent mutation is exon14 deletion. The resulting MET∆14 kinase is not constitutively active but requires HGF. The response to the ligand is stronger and long-lasting, protecting cancer cells from apoptosis and driving invasive ...
Marina Cerqua +8 more
doaj +2 more sources
FER kinase governs invasive growth of head and neck squamous cell carcinoma through dynamic control of growth factor receptor activity [PDF]
Neoplasia: An International Journal for Oncology ResearchPromiscuous activation of growth factor receptors drives sustained MAP kinase signaling, which reinforces oncogene addiction in HPV-negative head and neck squamous cell carcinoma (HNSCC).
Peter D. Haughton +13 more
doaj +2 more sources
The Mitochondrial GTPase Gem1 Contributes to the Cell Wall Stress Response and Invasive Growth of Candida albicans [PDF]
Frontiers in Microbiology, 2017 The interactions of mitochondria with the endoplasmic reticulum (ER) are crucial for maintaining proper mitochondrial morphology, function and dynamics.
Barbara Koch +5 more
doaj +2 more sources
STAT6 expression in glioblastoma promotes invasive growth [PDF]
BMC Cancer, 2011 Background Glioblastoma (GBM) is a highly aggressive malignant primary brain tumor, characterized by rapid growth, diffuse infiltration of cells into both adjacent and remote brain regions, and a generalized resistance to currently available treatment ...
Silva Corinne M +4 more
doaj +3 more sources
Filamentous invasive growth of mutants of the genes encoding ammonia-metabolizing enzymes in the fission yeast Schizosaccharomyces pombe. [PDF]
PLoS ONE, 2017 The fission yeast Schizosaccharomyces pombe undergoes a switch from yeast to filamentous invasive growth in response to certain environmental stimuli. Among them is ammonium limitation.
Yoshie Sasaki +3 more
doaj +2 more sources
Antioxidants, 2021 Reactive oxygen species (ROS) that exceed the antioxidative capacity of the cell can be harmful and are termed oxidative stress. Increasing evidence suggests that ROS are not exclusively detrimental, but can fulfill important signaling functions ...
Manuela Weber +10 more
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Integrins in invasive growth [PDF]
Journal of Clinical Investigation, 2002 Udgivelsesdato: 2002 ...
Brakebusch, Cord +4 more
openaire +5 more sources
Research Progress on Growth Characteristics of Invasive Plants in Different Habitats [PDF]
E3S Web of Conferences, 2021 Biological invasion generates serious threats to global biodiversity. Exotic species usually have high environmental adaptability and tolerance, which is one of the bases of their invasion.
Wang Zhe, Yue Ruirui, Li Yang
doaj +1 more source
Methodological approaches for unraveling ill-natured moments of generally good-natured Saccharomyces cerevisiae [PDF]
Zbornik Matice Srpske za Prirodne Nauke, 2013 The yeast Saccharomyces cerevisiae is a two-sided coin; it has a beneficial, biotechnological value with a strong connotation of reliable safety, but also a negative, potentially pathogenic nature on the other hand.
Zupan Jure +3 more
doaj +1 more source
BMC Endocrine Disorders, 2021 Background The prevalence of obesity is considered to be increased worldwide. Lack of mineral elements is one of the essential side effects of bariatric surgery as a trending treatment for obesity.
Fahimeh Soheilipour +7 more
doaj +1 more source