ABSTRACT Prior pharmacokinetic (PK) analysis revealed that increased alpha‐1‐acid glycoprotein (AAG) levels are associated with decreased imatinib unbound fraction in coronavirus disease 2019 (COVID‐19) patients. This study aimed to investigate the PK of total and unbound concentrations of imatinib and the metabolite N‐desmethyl imatinib in ...
Medhat M. Said +10 more
wiley +1 more source
Delirium in critically ill COVID-19 patients: incidence, predictors, and outcomes in invasive mechanical ventilation with versus without ECMO support. [PDF]
Seeger S +8 more
europepmc +1 more source
Summary This pilot randomised feasibility trial evaluated the feasibility and acceptability of early, intensive home‐based pulmonary rehabilitation (PR) and high‐flow nasal oxygen (HFO) during exercise in patients with exertional hypoxaemia post‐hospitalisation. Early home‐based PR was feasible and safe.
Yingjuan Mok +11 more
wiley +1 more source
Clinical Profiles and Prognostic Patterns in Critically Ill Cardiac Patients Requiring Invasive Mechanical Ventilation: A Five-Year Retrospective Cohort Study. [PDF]
Macovei L +4 more
europepmc +1 more source
Camels as a Climate‐Resilient Linchpin for Sustainable Development in Global Drylands
ABSTRACT Camels represent a significant, yet underutilized, asset for advancing integrated sustainable development in the world's expanding drylands. Previous reviews have examined camels' physiology, milk composition, or pastoral systems in isolation; this review examines their potential as a climate‐resilient linchpin for food systems by synthesizing
Ayana Angassa +2 more
wiley +1 more source
To: The efficacy of high-flow nasal cannula versus non-invasive mechanical ventilation in preventing reintubation in patients at high risk of extubation failure: systematic review and meta-analysis with trial sequential analysis. [PDF]
Bayraktar YŞ.
europepmc +1 more source
This prospective study developed a two‐step clinical scoring system for obstructive sleep apnea (OSA) screening based on patients’ somesthetic perception of oropharyngeal airflow. The Intermediate Score (IS ≥ 7.5) achieved 73% sensitivity and 77% specificity (AUC = 0.7754; OR = 8.96).
Cédric Garcion +4 more
wiley +1 more source
Research Progress on Thermal Runaway and Thermal Management of Lithium‐Ion Batteries
This review summarizes thermal runaway mechanisms, propagation pathways, mitigation strategies, and intelligent thermal management technologies for lithium‐ion batteries, highlighting the transition from passive heat dissipation to integrated safety regulation through advanced cooling, barrier materials, sensing, machine learning, and digital‐twin ...
Songrong Li +4 more
wiley +1 more source
Nomogram-based prediction model for extubation failure in preterm infants with invasive mechanical ventilation. [PDF]
Tan C, Sui Y, Wang L.
europepmc +1 more source
Nonthermal plasma approaches for combating implant‐associated infections: A compendious review
Implant‐associated infections pose serious clinical challenges. Non‐thermal plasma (NTP) modifications overcome this bottleneck in distinct ways relative to traditional sterilization methods. Gas‐phase plasmas generate highly energetic species, UV radiation and reactive oxygen/nitrogen species (RONS), which alter the implant surface properties.
A. M. Trimukhe +8 more
wiley +1 more source

