Results 231 to 240 of about 156,339 (303)

Nanobody–chlorin e6 conjugate for Nectin‐4‐mediated tumor targeting and enhanced photodynamic therapy

VIEW, EarlyView.
Nectin‐4 is frequently overexpressed in solid tumors, yet many PDT photosensitizers show poor water solubility and nonspecific uptake. A Nectin‐4‐targeted nanobody–chlorin e6 conjugate (NPC) improves aqueous solubility and selectively accumulates in Nectin‐4‐positive tumor cells.
Haodian Wan, Tao Ye, Yawei Bi, Jiayu Zhang, Wei Wu, Aochi Liu, Li Sun, Jie Lin, Ningli Chai, Manjie Zhang, Jian Ma   +10 more
wiley   +1 more source

AI Model Based on Diaphragm Ultrasound to Improve the Predictive Performance of Invasive Mechanical Ventilation Weaning: Prospective Cohort Study. [PDF]

JMIR Form Res
Song F, Liu H, Ma H, Chen X, Wang S, Qin T, Liang H, Huang D.   +7 more
europepmc   +1 more source

Modeling the lung‒brain axis in critical illness: Multifactorial crosstalk through organoids and organ‐on‐a‐chip system

VIEW, EarlyView.
Patients in intensive care units often experience lung injuries, complicated by brain problems. Advanced laboratory tools, organoids, and organs‐on‐chips facilitated the study of multiorgan interactions, help us understand the communication between the lungs and brain.
Wanyi Zhang, Ting Wang, Mengying Yao, Longxiang Su, Lixin Xie, Pan Pan   +5 more
wiley   +1 more source

Fast Variational Bayesian Inference for Correlated Survival Data: An Application to Invasive Mechanical Ventilation Duration Analysis. [PDF]

Stat Med
Xian C, P E de Souza C, He W, Rodrigues FF, Tian R.   +4 more
europepmc   +1 more source

Epiglottis Collapse in Individuals With Obstructive Sleep Apnea

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Obstructive sleep apnea (OSA) is a common sleep disorder characterized by repeated upper airway collapse during sleep. The epiglottis, often overlooked in conventional assessments, has emerged as a site of significant obstruction in OSA.
Dan Chen, Li Zhou, Qi‐Ying Zeng, Yu‐Yin Liu, Jia‐Jing Yang, Rui Liu, Zhi‐Hang Zhou, Fei‐Fei Chen, Li Tang, Fang‐Qi Liang, Hong‐Liang Yi, Su‐Ru Liu   +11 more
wiley   +1 more source

Chinese Guidelines for the Diagnosis and Surgical Treatment of Adult Obstructive Sleep Apnea (2024)

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Obstructive sleep apnea (OSA) is a common chronic disorder characterized by abnormal breathing during sleeping. OSA can damage various organs throughout the body and is burdensome, both socially and economically. Moreover, as OSA has been increasingly studied in recent years, new evidence‐based guidelines for its diagnosis and surgical ...
Working Group of Guideline for the Diagnosis and Surgical Treatment of Adult OSA, Subspecialty Group of Laryngopharyngology, Society of Otorhinolaryngology Head and Neck Surgery, Chinese Medical Association, Subspecialty Group of Voice, Society of Otorhinolaryngology Head and Neck Surgery, Chinese Medical Association, Editorial Board of Chinese Journal of Otorhinolaryngology Head and Neck Surgery   +7 more
wiley   +1 more source

Bedside Assessment of the Respiratory System During Invasive Mechanical Ventilation. [PDF]

J Clin Med
Giosa L, Collins PD, Shetty S, Lubian M, Del Signore R, Chioccola M, Pugliese F, Camporota L, Camporota L.   +8 more
europepmc   +1 more source

Determinants of Compliance to Enhanced Recovery Protocol After Emergency Laparotomy

World Journal of Surgery, EarlyView.
Enhanced Recovery protocols (ERP) are comprehensive, evidence‐based approaches aimed at accelerating patient recovery and improving surgical results; increasing evidence exists about their adoption in emergency laparotomy. The study aimed to evaluate the compliance to the proposed postoperative pathway and the determinants of late recovery.
Marco Ceresoli, Chiara Fumagalli, Alan Biloslavo, Antonio La Greca, Michele Carlucci, Giovanni Pesenti, Savino Occhionorelli, Pietro Bisagni, Carlo Feo, Dario Tartaglia, Dario Parini, Matteo Runfola, Riccardo Somigli, Diego Visconti, Diego Mariani, Diletta Cassini, Andrea Mingoli, Marco Braga, On behalf of the Study Collaborative Group   +18 more
wiley   +1 more source

Expert consensus-based clinical practice guidelines for Care and weaning procedures in tracheostomized ICU patients after invasive mechanical ventilation: a joint statement by the Intensive Care Physiotherapy Society (SKR) and the French Intensive Care Society (SRLF). [PDF]

Ann Intensive Care
Medrinal C, Delemazure J, Billard M, Carpentier D, Choukroun G, Combret Y, De Crouy AC, López CD, Dugernier J, Farcy M, Foudhaili A, Gallice T, Gatignol P, Ghelab Z, Houze MH, Jezequel M, Latiers AC, Marzouk M, Morawiec E, Piquilloud L, Ruttimann A, Sanchez P, Terzi N, Thille AW, Reffienna M.   +24 more
europepmc   +1 more source

Guidelines for Essential Trauma Care: Second Edition (2026)

World Journal of Surgery, EarlyView.
Injury is a major cause of death and disability globally, with the highest burden in low‐ and middle‐income countries (LMICs). Strengthening the organization and planning for trauma care (care of the injured) can improve care and lower mortality. In 2004, the International Association for Trauma Surgery and Intensive Care (IATSIC) and the World Health ...
Charles Mock, Timothy C. Hardcastle, Christine Gaarder, Amit Gupta, Adam Gyedu, Manjul Joshipura, Elmin Steyn, on behalf of the Essential Trauma Care revision author group, Valencia Adjei, Roger Alcock, Vanda Amado, Michael Boampong, Sanjeev Booi, Petra Brysiewicz, Corazon Cabanilla‐Manuntag, Cristiane de Alencar Domingues, Ghada Elhadary, Ranjith Nanda Ellawala, Sarnai Erdene, Ama Akoma Essuman, Jorge Esteban Foianini, Filippo Gatti, Armando Garcia Guererra, Greg Hynes, Adil Haider, Sandy Ingless, Balavenkata Jagannathan, Helen Jowett, Knut Magne Kolstadbråten, Sonja Krofak, Aireen Patricia Madrid, Tina Tomić Mahečić, Claude Martin, Daniel Ntogwrachu, Bisola Onajin‐Obembe, Nhobojit Roy, Andres Rubiano, Niisoja Mensah Torto, Ben Wachira, Meg Walmsley, Torben Wisborg, Elma Wong   +41 more
wiley   +1 more source