Results 31 to 40 of about 91,240 (240)

Invasive and Non-invasive Mechanical Ventilation in Pediatric Patients with COVID-19: A Systematic Review

Journal of Mazandaran University of Medical Sciences, 2020
Background and purpose: In the last months of 2019, the new coronavirus infection (COVID-19) spread worldwide. This study investigated the need for mechanical ventilation in children who were admitted for COVID-19.
Mohammad Reza Navaeifar, Behzad Haghighi Aski, Bahareh Tohidi Rad, Mohammad Sadegh Rezai   +3 more
doaj  

Non-invasive respiratory support for preterm infants following extubation from mechanical ventilation. A narrative review and guideline suggestion

Pediatrics and Neonatology, 2020
The recent introduction of different non-invasive ventilation modes for preterm has decreased the need for intubation, invasive ventilation and sedation. However, specific guidelines for each non-invasive mode are still lacking.
Ammar M.H. Shehadeh
doaj   +1 more source

The characteristics and clinical course of patients with COVID-19 who received invasive mechanical ventilation in Osaka, Japan

International Journal of Infectious Diseases, 2021
Objective: To describe the detailed clinical course of patients with coronavirus disease 2019 (COVID-19) who received invasive mechanical ventilation.
Atsushi Hirayama, Jun Masui, Ayumi Murayama, Satomi Fujita, Jun Okamoto, Jun Tanaka, Takanori Hirayama, Toshitake Ohara, Emma Nakagawa Hoffmann, Jingwen Zhang, Haruna Kawachi, Hideo Okuno, Shigeto Hamaguchi, Kazunori Tomono, Rumiko Asada   +14 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Trends in clinical characteristics and outcomes of all critically ill COVID-19 adult patients hospitalized in France between March 2020 and June 2021: a national database study

Annals of Intensive Care, 2023
Introduction Studies regarding coronavirus disease 2019 (COVID-19) were mainly performed in the initial wave, but some small-scale data points to prognostic differences for patients in successive waves.
Diane Naouri, Albert Vuagnat, Gaëtan Beduneau, Martin Dres, Tai Pham, Alain Mercat, Alain Combes, Alexandre Demoule, Antoine Kimmoun, Matthieu Schmidt, Matthieu Jamme   +10 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Protective technologies of modern methods of respiratory support in neonatal practice

Вестник анестезиологии и реаниматологии, 2023
The article  presents  an analysis of literature data  on modern  protective regimens  for invasive respiratory support  in premature newborns  with respiratory distress  syndrome. We have considered positive and negative  aspects of the used methods  of
V. E. Ryumin, S. V. Kinzhalova, G. N. Chistyakova, I. I. Remizova, P. A. Kadochnikova   +4 more
doaj   +1 more source

Non-invasive mechanical ventilation in Spanish neonatal units

Anales de Pediatría (English Edition), 2022
Enquesta nacional; Ventilació mecànica no invasiva; Unitats de nounats ...
Fernandez Garcia, Cristina, Comuñas Gómez, Juan José, Montaner Ramón, Alicia, Camba Longueira, Fátima, Castillo Salinas, Félix   +4 more
openaire   +4 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source