Results 51 to 60 of about 3,338,677 (297)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Investigation of status quo of pulmonary atelectasis in neonates with mechanical ventilation and its influencing factors

Huli yanjiu, 2021
ObjectiveTo investigate the incidence of atelectasis in neonates with mechanical ventilation and analyze the influencing factors.MethodsThe neonates with mechanical ventilation，who were hospitalized in neonatal intensive care unit（NICU） of a Children's ...
TAN Wangyang, ZHANG Shuwen, LI Liling, LYU Tianchan, JI Futing, CAO Yun, HU Xiaojing   +6 more
doaj  

Validation of mechanical ventilation coding in hospital discharge abstracts: a population data linkage study

International Journal of Population Data Science, 2018
Introduction Mechanical ventilation (MV) is an important intervention used in critically ill patients. Accurately identifying MV use in Hospital Discharge Abstracts will be extremely useful in population-based research.
Yao Nie, Kendiss Olafson, Jitender Sareen, Marina Yogendran   +3 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Invasive and Non-invasive Mechanical Ventilation in Pediatric Patients with COVID-19: A Systematic Review

Journal of Mazandaran University of Medical Sciences, 2020
Background and purpose: In the last months of 2019, the new coronavirus infection (COVID-19) spread worldwide. This study investigated the need for mechanical ventilation in children who were admitted for COVID-19.
Mohammad Reza Navaeifar, Behzad Haghighi Aski, Bahareh Tohidi Rad, Mohammad Sadegh Rezai   +3 more
doaj  

Trends in clinical characteristics and outcomes of all critically ill COVID-19 adult patients hospitalized in France between March 2020 and June 2021: a national database study

Annals of Intensive Care, 2023
Introduction Studies regarding coronavirus disease 2019 (COVID-19) were mainly performed in the initial wave, but some small-scale data points to prognostic differences for patients in successive waves.
Diane Naouri, Albert Vuagnat, Gaëtan Beduneau, Martin Dres, Tai Pham, Alain Mercat, Alain Combes, Alexandre Demoule, Antoine Kimmoun, Matthieu Schmidt, Matthieu Jamme   +10 more
doaj   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Correlations of mechanical power and its components with age and its interference in the outcome of SARS-CoV-2 in subjects undergoing pressure-controlled ventilation

, 2022
Introduction SARS-CoV-2 may be associated with ARDS and the VILI. However, there are still doubts about the correlations and the interference of tidal energy in the outcomes.
Claudio Luciano Franck, Gustavo Maysonnave Franck, Ehab G. Daoud   +2 more
core   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source

Robust, maintainable, emergency invasive mechanical ventilator

Revista Brasileira de Terapia Intensiva, 2022
To develop a simple, robust, safe and efficient invasive mechanical ventilator that can be used in remote areas of the world or war zones where the practical utility of more sophisticated equipment is limited by considerations of maintainability, availability of parts, transportation and/or cost.The device implements the pressure-controlled continuous ...
Fonte, Paulo J. R., Martinho, Alberto, Pereira, Américo, Gomes, Andreia, Neves, Ângela, Abrunhosa, Antero, Bugalho, António, Gabriel-Santos, António, Grilo, António, Carmo, Carlos, Maltez, Elsa, do Nascimento, João Agostinho, Goes, João, Martins, João, Oliveira, João Pedro, Pimenta, Jorge, Santos, José Paulo, Gil, Luís C., Lopes, Luís, Pimenta, Mário, Moreira, Olga, Cunha, Orlando, de Sousa, Pedro Pinheiro, Póvoa, Pedro, Cavaco-Gonçalves, Sandra, Barroso, Susana, Santos, Telmo G.   +26 more
openaire   +2 more sources