Results 61 to 70 of about 3,508,285 (256)

Making Sweat Measurable: Induction, Sampling, and Refreshment in Wearable Biofluid Sensing

Advanced Science, EarlyView.
Wearable sweat sensing relies not only on chemical detection but also on controlled biofluid management. This Review integrates sweat physiology, induction strategies, and microfluidic sampling architectures, demonstrating how flux, transport, and refreshment shape measurement reliability.
Soyoung Shin, Wei Gao
wiley   +1 more source

Programmable Paracrine‐Mimetic Microneedle System for Temporal Regulation of Cardiac Repair

Advanced Science, EarlyView.
Temporal signaling is encoded into a programmable paracrine‐mimetic microneedle patch via tris(2,2'‐bipyridyl)dichlororuthenium(II) hexahydrate/sodium persulfate‐tuned hydrogel microparticles that deliver TGF‐β, IGF‐1, and VEGF over phase‐matched 7‐, 14‐, and 28‐day windows.
Yichen Dai, Pengchong Du, Zhaoyang Wang, Surilige, Rangga Fokta, Renjian Tan, Xiqing Zhao, Shuoyi Zhang, Yuecheng Wang, Yixin Zhang, Ziliang Fu, Rui Gong, Cheng Jiang, Yisheng He, Qiguang Wang, Renke Li, Khoon Lim, Junnan Tang, Xiaolin Cui   +18 more
wiley   +1 more source

Encapsulated Leptin‐Producing Cells Facilitate Entrainment of Circadian Rhythms in Rodents and Nonhuman Primates

Advanced Science, EarlyView.
A clinically translatable cell line can be engineered to produce leptin, encapsulated in biomaterial and safely implanted to produce and deliver the metabolic regulating protein within the body. Implantation of these encapsulated cells decreases the time it takes for mice and non‐human primates to adjust to circadian disruptions similar to those ...
Samantha T. Fleury, Xuanyi Lin, Peter D. Rios, Christopher Olker, Eun Joo Song, Alejandra Cobos Perez, Cody Fell, Daisy Lopez, Ira Joshi, Hafsa Nasir, Cecelia Curtis, Danna Muringi, Kaiyuan Wang, José Oberholzer, Fred W. Turek, Isaac B. Hilton, Jonathan Rivnay, Martha Hotz Vitaterna, Omid Veiseh   +18 more
wiley   +1 more source

Home Mechanical Ventilation in Children: Erciyes University Experience

, 2017
Objective: In this study it was aimed to share experiences and to draw attention to the problems about home mechanical ventilation (HMV) which is used in the treatment of patients with chronic respiratory failure and is increasingly becoming widespread ...
ÜLGEN TEKEREK, Nazan, Adem Dursun, Başak Nur Akyıldız, AKYILDIZ, Başaknur, Nazan Ülgen Tekerek, DURSUN, Adem   +5 more
core   +1 more source

Characteristics and outcomes of COVID-19 patients requiring invasive mechanical ventilation vs intubated non-COVID-19.

, 2023
Characteristics and outcomes of COVID-19 patients requiring invasive mechanical ventilation vs intubated non-COVID-19.
Kyle Chapman (14768530), Edward Rojas (14768524), Rahul Sangani (14768527), Carlo Avalon (14768533), Sunil Sharma (435513), Varun Badami (14768521), Sijin Wen (38922), Austin King (12483029)   +7 more
core   +1 more source

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

Advanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang, Zijian Zhang, Fulin Dai, Zhijie Yin, Zhen Xing, Yurong Li, Haochong Lei, Junfeng Zhang, Chunyan Liu, Yan Li, Lei Dong   +10 more
wiley   +1 more source

GRADE summary of findings table of mortality, progression to invasive mechanical ventilation, and serious adverse events.

, 2023
GRADE summary of findings table of mortality, progression to invasive mechanical ventilation, and serious adverse events.
Miyoung Choi (8153172), Dae-Hyup Koh (12302237), Su-Yeon Yu (12302234), Kyungmin Huh (5636111), Seungeun Ryoo (12302240), Joon-Sup Yeom (7323032), Jung Yeon Heo (8988050)   +6 more
core   +1 more source

Targeting LDHA Palmitoylation Sensitizes GBM to Chemoradiotherapy via Suppressing Palmitic Acid Induced Glycolytic Reprogramming

Advanced Science, EarlyView.
Mesenchymal GSCs preferentially uptake palmitic acid, thereby promoting ZDHHC12‐mediated LDHA palmitoylation. This modification enhances LDHA enzymatic activity, drives glycolytic reprogramming, and facilitates exosomal LDHA‐mediated TAM regulation.
Zijie Gao, Rongrong Zhao, Zheyuan Chen, Qingtong Wang, Huanyu Yang, Boyan Li, Yanhua Qi, Shulin Zhao, Jixing Zhao, Jiawei Qiu, Ziwen Pan, Zhe Han, Ruochuan Li, Huize Xia, Weijie Tang, Xing Guo, Ping Zhang, Hongyu Zhao, Xu Qian, Gang Li, Hao Xue   +20 more
wiley   +1 more source

Chronic Stress Promotes Gastric Cancer Metastasis by Inducing Microbiota‐Associated Kynurenine Accumulation and Macrophage Remodeling

Advanced Science, EarlyView.
Chronic stress reshapes the gut microbiota and enriches Lactobacillus reuteri, promoting microbiota‐associated kynurenine accumulation through altered tryptophan metabolism. Kynurenine drives immunosuppressive remodeling of tumor‐associated macrophages through TNFR2–C/EBPβ signaling, thereby enhancing gastric cancer dissemination.
Sicheng Zhao, Zhiyuan Song, Jingcheng Zhang, Jiaheng Lou, Shuo Zhang, Boqiang Liu, Yunhai Wei, Fengmei Qiu, Tao Jiang, Guangji Zhang   +9 more
wiley   +1 more source

Outcomes of mechanically ventilated patients with COVID-19 associated respiratory failure.

PLoS ONE, 2020
PurposeThe outcomes of patients requiring invasive mechanical ventilation for COVID-19 remain poorly defined. We sought to determine clinical characteristics and outcomes of patients with COVID-19 managed with invasive mechanical ventilation in an ...
Christopher S King, Dhwani Sahjwani, A Whitney Brown, Saad Feroz, Paula Cameron, Erik Osborn, Mehul Desai, Svetolik Djurkovic, Aditya Kasarabada, Rachel Hinerman, James Lantry, Oksana A Shlobin, Kareem Ahmad, Vikramjit Khangoora, Shambhu Aryal, A Claire Collins, Alan Speir, Steven Nathan   +17 more
doaj   +1 more source