Results 61 to 70 of about 156,339 (303)

Practical aspects on the use of non-invasive respiratory support in preterm infants

International Journal of Pediatrics & Adolescent Medicine, 2020
Preterm infants frequently present with respiratory insufficiency requiring respiratory assistance. Invasive mechanical ventilation has been associated with several short and long term complications.
Nehad Nasef, Hend ME. Rashed, Hany Aly
doaj   +1 more source

Successful Extracorporeal Life Support for Life-threatening Hypercapnia with Bronchiolitis Obliterans after Allogeneic Hematopoietic Stem Cell Transplantation [PDF]

, 2011
Bronchiolitis obliterans (BO) is a disease with a poor prognosis, and a key factor that limits long-term survival after allogeneic hematopoietic stem cell transplantation (HSCT).
Ichiba, Shingo, Kanehiro, Arihiko, Maeda, Yoshinobu, Miyahara, Nobuaki, Murakami, Toshi, Nagano, Osamu, Ochi, Nobuaki, Tanimoto, Mitsune, Tanimoto, Yasushi, Terado, Michihisa, Ujike, Yoshihito, Waseda, Koichi   +11 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Non-invasive respiratory support for preterm infants following extubation from mechanical ventilation. A narrative review and guideline suggestion

Pediatrics and Neonatology, 2020
The recent introduction of different non-invasive ventilation modes for preterm has decreased the need for intubation, invasive ventilation and sedation. However, specific guidelines for each non-invasive mode are still lacking.
Ammar M.H. Shehadeh
doaj   +1 more source

The characteristics and clinical course of patients with COVID-19 who received invasive mechanical ventilation in Osaka, Japan

International Journal of Infectious Diseases, 2021
Objective: To describe the detailed clinical course of patients with coronavirus disease 2019 (COVID-19) who received invasive mechanical ventilation.
Atsushi Hirayama, Jun Masui, Ayumi Murayama, Satomi Fujita, Jun Okamoto, Jun Tanaka, Takanori Hirayama, Toshitake Ohara, Emma Nakagawa Hoffmann, Jingwen Zhang, Haruna Kawachi, Hideo Okuno, Shigeto Hamaguchi, Kazunori Tomono, Rumiko Asada   +14 more
doaj   +1 more source

Prone position: Does it help with acute respiratory distress syndrome (ARDS) requiring extracorporeal membrane oxygenation (ECMO)? [PDF]

, 2017
Introduction: Lung protective ventilation therapy with low tidal volume-high PEEP is the standard treatment for the patients with acute respiratory distress syndrome (ARDS).
Azimzadeh, Nava, Baram, Michael, Cavarocchi, Nicholas C., Hirose, Hitoshi   +3 more
core   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Protective technologies of modern methods of respiratory support in neonatal practice

Вестник анестезиологии и реаниматологии, 2023
The article  presents  an analysis of literature data  on modern  protective regimens  for invasive respiratory support  in premature newborns  with respiratory distress  syndrome. We have considered positive and negative  aspects of the used methods  of
V. E. Ryumin, S. V. Kinzhalova, G. N. Chistyakova, I. I. Remizova, P. A. Kadochnikova   +4 more
doaj   +1 more source

Hypocapnia Alone Fails to Provoke Important Electrocardiogram Changes in Coronary Artery Diseased Patients [PDF]

, 2019
Background: There is still an urgent clinical need to develop non-invasive diagnostic tests for early ischemic heart disease because, once angina occurs, it is too late. Hypocapnia has long been known to cause coronary artery vasoconstriction.
Broch, Christensen, Cooper, Cooper, Crystal, Fischer, Freeman, Golden, Guensch, Haarstad, Joy, Kenigsberg, Kruyswijk, Levy, Levy, McCance, Neill, Parkes, Parkes, Parkes, Parkes, Pepine, Rautaharju, Rowe, Rutherford, Sheppard, Stewart, Surawicz, Surawicz, Turner, Van Ooteghem, Wagner, Wagner, Wasserburger, West, Yokoyama   +35 more
core   +3 more sources