Fosmanogepix (APX001) Is Effective in the Treatment of Immunocompromised Mice Infected with Invasive Pulmonary Scedosporiosis or Disseminated Fusariosis. [PDF]
There are limited treatment options for immunosuppressed patients with lethal invasive fungal infections due to Fusarium and Scedosporium Manogepix (MGX; APX001A) is a novel antifungal that targets the conserved Gwt1 enzyme required for localization of ...
Alkhazraji, Sondus +8 more
core +1 more source
Invasive pulmonary aspergillosis in patients with acute respiratory syndrome by COVID-19
Cyntia Sánchez Martín +5 more
openalex +2 more sources
Galactomannan Does Not Precede Major Signs on a Pulmonary Computerized Tomographic Scan Suggestive of Invasive Aspergillosis in Patients with Hematological Malignancies [PDF]
Background. Detection of serum galactomannan (GM) antigen and presence of the halo sign on a pulmonary computerized tomographic (CT) scan have a high specificity but a low sensitivity to diagnose invasive aspergillosis (IA) in patients at risk for this ...
Buitrago, C. +10 more
core
[Invasive pulmonary aspergillosis in influenza]. [PDF]
BACKGROUND: Invasive pulmonary aspergillosis (IPA) is a life-threatening infection that occurs predominantly in severely immunocompromised patients. Recently, IPA is also increasingly seen in less severely immunocompromised patients, such as patients with COPD receiving glucocorticoids and patients on ventilation in an IC unit.
Kolwijck, E. +5 more
openaire +2 more sources
Treatment and timing in invasive mould disease [PDF]
Invasive mould disease is a growing threat for immunocompromised patients. The optimum time to use mould-active antifungal agents is much debated. Current approaches to antifungal prophylaxis, early treatment (empirical and pre-emptive therapy) and ...
Cordonnier, Catherine +5 more
core
Improving survival of acute-on-chronic liver failure patients complicated with invasive pulmonary aspergillosis [PDF]
Jie Gao +13 more
openalex +1 more source
Variability of voriconazole plasma levels measured by new high-performance liquid chromatography and bioassay methods, [and] Voriconazole therapeutic drug monitoring in patients with invasive mycoses improves efficacy and safety outcomes [PDF]
Rapport de synthèse1. Partie de laboratoireCette première étude décrit le développement et la validation, selon les standards internationaux, de deux techniques de mesure des concentrations sanguines de voriconazole, un nouvel agent antifongique à large ...
Pascual, A.
core
Recent Developments in Inhaled Triazoles Against Invasive Pulmonary Aspergillosis [PDF]
Romain Merlos +2 more
openalex +1 more source

