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Pulmonary aspergillosis: diagnosis and treatment
Aspergillus species are the most frequent cause of fungal infections of the lungs with a broad spectrum of clinical presentations including invasive pulmonary aspergillosis (IPA) and chronic pulmonary aspergillosis (CPA).
Frederic Lamoth, Thierry Calandra
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Invasive Pulmonary Aspergillosis
Invasive pulmonary aspergillosis is growing in incidence, as patients at risk are growing in diversity. Outside the classical context of neutropenia, new risk factors are emerging or newly identified, such as new anticancer drugs, viral pneumonias and ...
Marie-Pierre Ledoux, R. Herbrecht
semanticscholar +4 more sources
Rationale Invasive pulmonary aspergillosis has emerged as a frequent coinfection in severe coronavirus disease (COVID-19), similarly to influenza, yet the clinical invasiveness is more debated.
L. Vanderbeke +17 more
semanticscholar +3 more sources
A Case Report of Immune Checkpoint Inhibitor-Associated Pneumonia Complicated by Invasive Pulmonary Aspergillosis in a Patient With Chronic Obstructive Pulmonary Disease. [PDF]
ABSTRACT This case reports a patient with chronic obstructive pulmonary disease who developed immune checkpoint inhibitor‐associated pneumonia following immunotherapy, complicated by invasive pulmonary aspergillosis. Such cases are rare and pose diagnostic challenges in clinical practice. The successful diagnosis and treatment of this patient provide a
Lin S.
europepmc +2 more sources
Species within the Aspergillus spp. cause a wide range of infections in humans, including invasive pulmonary aspergillosis, chronic pulmonary aspergillosis, and allergic bronchopulmonary aspergillosis, and are associated with high mortality rates.
Liuyang Cai +14 more
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Invasive pulmonary aspergillosis in critically ill patients with pneumonia due to COVID-19, influenza, and communityacquired pneumonia: A prospective observational study [PDF]
Background and Purpose: Influenza A and SARS-CoV-2 are risk factors for invasive pulmonary aspergillosis. Both influenza-associated pulmonary aspergillosis and COVID-19-associated pulmonary aspergillosis result in high mortality and poor clinical ...
Ahsan Syed +7 more
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This study aimed to obtain further in-depth information on the value of metagenomic next-generation sequencing (mNGS) for diagnosing pulmonary aspergillosis in non-neutropenic patients.
Shujun Bao +4 more
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Timely diagnosis remains an unmet need in non-neutropenic patients at risk for aspergillosis, including those with COVID-19-associated pulmonary aspergillosis (CAPA), which in its early stages is characterized by tissue-invasive growth of the lungs with ...
M. Hoenigl +6 more
semanticscholar +1 more source
Invasive pulmonary aspergillosis in the intensive care unit: current challenges and best practices
The prevalence of invasive pulmonary aspergillosis (IPA) is growing in critically ill patients in the intensive care unit (ICU). It is increasingly recognized in immunocompetent hosts and immunocompromised ones.
S. Gaffney +4 more
semanticscholar +1 more source
Chronic pulmonary aspergillosis - case series and review of Indian literature
Aspergillus species, especially Aspergillus fumigatus, can cause varied pulmonary manifestations depending on the host immune status and duration of infection. Chronic pulmonary aspergillosis (CPA) is an under-reported entity, and its diagnosis remains a
Vikas Marwah +6 more
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