Results 71 to 80 of about 788,664 (335)

Fluorescent probes for imaging and detection of plant hormones and their receptors

open access: yesAdvanced Agrochem
Exploring plant behavior at the cellular scale in a minimally invasive manner is critical to understanding plant adaptation to the environment. Phytohormones play vital regulatory roles in multiple aspects of plant growth and development and acclimation ...
Yiliang Chen   +6 more
doaj   +1 more source

Students Engineer Solution to Public Health Issue in Dominican Republic [PDF]

open access: yes, 2016
Student chapter of Engineers Without Borders dispatches to rural village to build invention that replaces open-fire ...
Rodrigues, Jill
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Extruder for food product (otak–otak) with heater and roll cutter [PDF]

open access: yes, 2017
Food extrusion is a form of extrusion used in food industries. It is a process by which a set of mixed ingredients are forced through an opening in a perforated plate or die with a design specific to the food, and is then cut to a specified size by ...
Abd. Manan, Abdul Shukur   +5 more
core  

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Substrate-based discovery of α-hydroxycarboxylic acid derivatives as potential herbicides targeting dihydroxyacid dehydratase

open access: yesNature Communications
Dihydroxyacid dehydratase (DHAD), a key enzyme in branched-chain amino acid synthesis in plants, is a promising yet unexploited herbicide target.
Bo He   +15 more
doaj   +1 more source

Searching for Ways to Improve for Calculation Method of Employer’s Profit as a Factor for Calculating Employee Invention Remuneration: Focused on Hypothetical Royalty Rate, Exclusivity Contribution Rate, Employee Invention’s Contribution Rate

open access: yesJournal of Intellectual Property
Supreme Court decision 2017Hu1304 has established an inherency doctrine in determining novelty. According to the decision, it is not enough to simply show the possibility or probability that something can be done to show prior art to be the same as the ...
Joohwan Lee
doaj   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

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