Results 91 to 100 of about 285,779 (275)
This study investigates the effect of high-skilled inventor emigration rate on growth rate of the country of origin (COO). Inventor emigrants represent the human capital that can generate highly innovative work.
Jisong Kim, Nah Youn Lee
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Theranostics is a way of treating illness that blends medicine with testing. Specific characteristics should be present in the best theranostic agents for cancer: (1) the drugs should be safe and non-toxic; (2) they should be able to treat cancer ...
Hannaneh Azimizonuzi +7 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Profile and influence of the successful fisher-Inventor of marine conservation technology
Anecdotally it is often said that fishers are the best inventors of marine conservation technologies. In this paper I describe case studies of Turtle Excluder Devices (TEDs) and dolphin conservation technology, offering empirical evidence that fishers ...
Jenkins Lekelia
doaj
NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 11) [PDF]
This continuing bibliography lists index for 3256 patents and patent applications introduced into the NASA scientific and technical informations system from January 1977 through June 1977.
core +1 more source
The new modelling facilities at parametric CAD programme [PDF]
Tato bakalářská práce se zabývá programy Autodesk Inventor Professional 2008 a Ansys Workbench. Cílem je seznámení se s pracovním prostředím a postupem práce v obou programech a jejich vzájemnou spoluprací.
Sedláčková, Petra
core
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Understanding the Doctrine of Patentable Subject Matter [PDF]
The doctrine of patentable subject matter precludes basic inventions such as abstract ideas and laws of nature from patent protection. However, current economic thinking of the patent systemstresses the necessity of rewarding pioneering inventors in ...
Chiou, Jing-Yuan
core

