Results 31 to 40 of about 48,027 (244)
Understanding the inventor team size: A view from “The Rice Theory”
International Studies of Economics, 2022 The inventor is a vital input in acquiring new technologies. Collaboration among inventors is an essential topic for scholars. Talhelm et al. proposed The Rice Theory, highlighting the cultural differences between rice and wheat regions.
Yixin Zhao, Qingqing Zong
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From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
The Development of Student Key Competencies while Studying Computer Science in Secondary School
International Journal of Research in E-Learning, 2015 a transition to a new humanistic paradigm of education as well as the results of the PISA 2012 study “Creative Problem Solving.” Contradictions between traditional skills and 21st century competencies of a school graduate are analyzed.
Taisiia Mukii
doaj
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
La mode par ses métiers : histoire et savoir des fabricants du second xixe siècle
In SituDuring the second half of the 19thcentury, at a time when the creation and consumption of fashion were being invested by industry, it is possible to note an abundant production of texts seeking to analyse the history of fashion.
Émilie Hammen
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Актуальні питання суспільних наук та історії медицини, 2018 Статья посвящена 80-летию профессора Триняк Николая Григорьеви- ча и освещает его биографические данные и личность врача, ученого-изобретателя и новатора в стенах Буковинского государственного медицинского университета. Научная новизна.
Тарас БОЙЧУК +1 more
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Revealing the intricate effect of collaboration on innovation. [PDF]
PLoS ONE, 2015 We studied the Japan and U.S. patent records of several decades to demonstrate the effect of collaboration on innovation. We found that statistically inventor teams slightly outperform solo inventors while company teams perform equally well as solo ...
Hiroyasu Inoue, Yang-Yu Liu
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
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