Results 51 to 60 of about 285,779 (275)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
External sources of clean technology: evidence from the clean development mechanism [PDF]
, 2013 New technology is fundamental to sustainable development. However, inventors from industrialized countries often refuse technology transfer because they worry about reverse-engineering. When can clean technology transfer succeed?
A Dechezleprêtre +33 more
core +2 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Partial interlaminar separation system for composites [PDF]
, 1980 This inventor relates to an interlaminar separation system for composites wherein a thin layer of a perforated foil film is interposed between adjacent laminae of a composite formed from prepreg tapes to thereby permit laminate adherence through the ...
Elber, W.
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
La mode par ses métiers : histoire et savoir des fabricants du second xixe siècle
In SituDuring the second half of the 19thcentury, at a time when the creation and consumption of fashion were being invested by industry, it is possible to note an abundant production of texts seeking to analyse the history of fashion.
Émilie Hammen
doaj +1 more source
WYDAJNOŚĆ IMPLEMENTACJI PODSTAWOWYCH METOD CAŁKOWANIA W ŚRODOWISKU APP INVENTOR
Informatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska, 2015 W niniejszym artykule dokonano porównania wydajności podstawowych metod całkowania zaimplementowanych w środowisku App Inventor oraz Java dla platformy Android.
Kamil Żyła
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
AI and corporeal knowledge: inventing and performing with prostheses and sonic organs
Frontiers in Computer ScienceThe mainstream development of AI for artistic expression thrives on predictive models that are supposedly capable of abstracting creative ideas and actions into computable features.
Marco Donnarumma, Marco Donnarumma
doaj +1 more source