Results 61 to 70 of about 48,027 (244)
Hicrî I. Asırda Hadis Uydurma Faaliyeti ve Hadis Uyduranların Tespiti
Türkiye Din Eğitimi Araştırmaları Dergisi, 2020 Hadis tarihinde çokça tartışılan konulardan birisi de hadis uydurma faaliyetinin başlangıcıdır. Tüm görüşlerin ortak noktası ise hicrî birinci asırda birleşiyor olmalarıdır.
Recep Emin Gül
doaj
Poljarnyj Vestnik: Norwegian Journal of Slavic Studies, 2001 This paper is an attempt to account for the following kind of para- phrasability: Edison invented the electric bulb - Edison was the inventor of the electric bulb. The proposal is that in the last sentence the holder of the first actant position has been
Lennart Lönngren
doaj +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
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Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Uncle Sam wants you to be the first-inventor-to-file for nanotechnology inventions
Nanotechnology Reviews, 2012 By the Leahy-Smith America Invents Act (AIA), the U.S. patent system is experiencing the most significant reform since the U.S. Patent Act was enacted some 60 years ago. This article focuses on one aspect of the AIA that has perhaps triggered the biggest
Garsson Ross Spencer, Pham Chinh H.
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Community structure in co-inventor networks affects time to first citation for patents
Applied Network Science, 2019 We have investigated community structure in the co-inventor network of a given cohort of patents and related this structure to the dynamics of how these patents acquire their first citation.
William Doonan +3 more
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