Results 121 to 130 of about 8,047 (306)

The interactive web-based program MSmonitor for self-management and multidisciplinary care in multiple sclerosis: concept, content, and pilot results

open access: yesPatient Preference and Adherence, 2015
Peter Joseph Jongen,1,2 Ludovicus G Sinnige,3 Björn M van Geel,4 Freek Verheul,5 Wim l Verhagen,6 Ruud A van der Kruijk,7 Reinoud Haverkamp,8 Hans M Schrijver,9 J Coby Baart,10 Leo H Visser,11 Edo P Arnoldus,12 H Jacobus Gilhuis,13 Paul Pop,14 ...
Jongen PJ   +17 more
doaj  

FGF13 Deficiency Ameliorates Paclitaxel‐Induced Neuropathic Pain by Inhibiting VASH1‐Mediated Microtubule Detyrosination to Promote Mitophagy

open access: yesAdvanced Science, EarlyView.
FGF13 is upregulated in DRG neurons of PIPNP model mice. DRG neuron‐specific knockout of FGF13 ameliorates PIPNP symptoms. Mechanistically, FGF13 potentiates microtubule detyrosination by promoting VASH1 binding to microtubules. FGF13 knockout suppresses VASH1‐mediated microtubule detyrosination and promotes α‐tubulin tyrosination.
Yiming Dong   +10 more
wiley   +1 more source

Logistic Stewardship: Supporting Antimicrobial Stewardship Programs Based on Antibiotics Goods Flow

open access: yesAntibiotics
Background/Objectives: Antimicrobial resistance is a global threat to safe health care, and a reduction in antibiotic consumption seems to be an appropriate preventive measure.
Bianca Leistner   +7 more
doaj   +1 more source

Psychometric properties of the Beck Youth Inventories in a sample of Icelandic children 10-15 year of age

open access: yes, 2009
Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/OpenSjálfsmatskvarðar Becks eru fimm kvarðar sem meta sjálfsmynd, kvíða, þunglyndi, reiði og hegðunarvanda hjá 7-18 ára bömum og unglingum.
Daníel Þór Ólason   +2 more
core  

Stress History Establishes a Transient Tolerant State That Shapes Antibiotic Survival Upon Resuscitation

open access: yesAdvanced Science, EarlyView.
High‐throughput single‐cell analysis of resuscitating bacteria reveals a starvation‐history‐dependent transiently tolerant subpopulation that survives β$\beta$‐lactam exposure by temporarily reducing growth. Distinct from classical persisters, these actively growing yet dynamically modulated cells dominate survival across clinically relevant antibiotic
Kieran Abbott   +5 more
wiley   +1 more source

Motivation for treatment in patients with substance use disorder: personal volunteering versus legal/familial enforcement

open access: yesNeuropsychiatric Disease and Treatment, 2014
Rabia Bilici,1 Esra Yazici,2 Ali Evren Tufan,3 Elif Mutlu,4 Filiz İzci,1 Görkem Karakas Ugurlu5 1Erenkoy Mental Health and Neurology Training and Research Hospital, Department of Psychiatry, Istanbul; 2Sakarya University, Medical Faculty ...
Bilici R   +5 more
doaj  

Diseño de un manual de control interno de inventarios basado en las NIIF para PYMES en el Hospital de Especialidades San Juan HOSPIESAJ S.A., de la ciudad de Riobamba, período 2011 [PDF]

open access: yes, 2013
La presente investigación contiene la propuesta de implementación de un manual de control de inventarios en base a las Normas Internacionales de Información Financiera para PYMES dentro del Hospital de Especialidades San Juan HOSPIESAJ
Quito Abad, Lily Fernanda
core  

Epithelial TRIM27 Inhibits Intestinal Inflammation in Ulcerative Colitis by the USP7/TRIM27‐IKK Double Negative‐Feedback

open access: yesAdvanced Science, EarlyView.
ABSTRACT The E3 ubiquitin ligase tripartite motif 27 (TRIM27) is a negative regulator of NF‐κB activation and the innate immune response, and TRIM27 deficiency significantly impairs dextran sulfate sodium (DSS)‐induced colitis. The function of TRIM27 in intestinal epithelial cells (IECs), the mechanism by which TRIM27 inhibits the NF‐κB pathway and its
Weimin Xu   +10 more
wiley   +1 more source

Srebra z ewangelickiego kościoła pw. św. Jerzego w Toruniu w świetle inwentarzy z lat 1580-1817

open access: yesKwartalnik Historii Kultury Materialnej, 2016
SILVER VESSELS FROM THE EVANGELICAL CHURCH OF ST GEORGE IN TORUŃ IN THE LIGHT OF INVENTORIES FROM THE YEARS 1580–1817 The article concerns silver liturgical vessels founded by parishioners in the modern period for St George’ church situated in the ...
Bartłomiej Łyczak
doaj  

Cigarette Smoke‐Induced Alveolar Macrophage Senescence via GEM/SIRT3‐Mediated Mitochondrial Dysfunction

open access: yesAdvanced Science, EarlyView.
Cigarette smoke accelerates the aging of immune cells in the lung. By combining human single‐cell sequencing, cell culture, and mouse models, the authors show that the protein GEM drives mitochondrial damage and senescence in alveolar macrophages by suppressing SIRT3.
Jin Wang   +8 more
wiley   +1 more source

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