Results 141 to 150 of about 2,359,633 (295)

Reducing healthcare emissions in the United States in the era of federal environmental deregulation: established and emerging mitigation opportunities and concomitant benefits. [PDF]

BMC Glob Public Health
Mascarenhas E, Fayanju OA, Arroyo AC, Tirumalasetty J.   +3 more
europepmc   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source

Leveraging an Antimicrobial Stewardship Collaborative and Urgent Care Center Medication-dispensing Kiosks to Support Shorter Antibiotic Durations: a Multisite, Retrospective Evaluation. [PDF]

Open Forum Infect Dis
Gauthier TP, Lobo EA, Frederick CM, Phan H, Russell LC, DeCoske M, Levine R, Ceballos Y, Sanz-Martinez E.   +8 more
europepmc   +1 more source

Mesoporous‐Shell Monolayer Plasmonic Architecture Enables Quantitative and Decision‐Guided SERS

Advanced Science, EarlyView.
Mesoporous‐shell‐regulated molecular transport combined with monolayer hotspot determinism transforms surface‐enhanced Raman spectroscopy (SERS) from ultrasensitive detection into quantitative and decision‐guided molecular sensing. ABSTRACT Quantitative surface‐enhanced Raman spectroscopy (SERS) has long been impeded by stochastic hotspot formation ...
Guangyao Huang, Ying Wang, Yue Fang, Jingyuan Shao, Sensen Hao, Mancun Zhao, Yuan Yao, Junping Wang, Wei Zhou, Hongzhi Wang   +9 more
wiley   +1 more source

Comparison of Commonly Applied Outcome Inventories as Measures of General Internalizing Pathology in Psychological Therapies. [PDF]

Clin Psychol Psychother
Lintula SJ, Saarni SE, Barkham M, Rosenström TH.   +3 more
europepmc   +1 more source

Modbury Hospital Bed Race photo

, 1990
Colour photo of various Modbury Hospital Bed Race running down the ...
Modbury Hospital
core  

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

Advanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang, Shuqin Xu, Zixuan Zhang, Chenwen Wan, Xiaoqin Wang, Peihua Wang, Huini Yang, Tianxiao Huang, Yijia Yuan, Faiza Atique, Rui Yang, Yingli He, Zhijun Liu   +12 more
wiley   +1 more source

Advancing Gut-Brain Axis Research in Parkinson's Disease: Addressing Measurement Heterogeneity and Baseline Cognitive Stratification. [PDF]

J Gastroenterol Hepatol
Zhang J, Dai W, Zhou P.
europepmc   +1 more source

Low SLC8A1 in Colorectal Cancer Dictates Radiotherapy Resistance Through Calcium‐Dependent ANXA2+sEVs Driving M2 Polarization of TAMs

Advanced Science, EarlyView.
SLC8A1 deficiency in colorectal cancer cells increases intracellular calcium signaling, promoting the secretion of ANXA2‐enriched small extracellular vesicles. These vesicles reprogram tumor‐associated macrophages towards an M2 phenotype, which in turn fosters a tumor microenvironment conducive to radioresistance and is associated with poor patient ...
Yimin Fang, Jinghan Zhu, Qian Xiao, Qichun Wei, Xiujing He, Ping Li, Kai Jiang, Yue Liu, Yeting Hu, Weiwei Yu, Chuansheng Guo, Sheng Chen, Jian Zhao, Siqi Dai, Jingsun Wei, Hang Yang, Tongtong Bu, Kefeng Ding, Haiyan Chen   +18 more
wiley   +1 more source

'The Tracker' - Modbury Hospital News

, 1985
A newsletter for Modbury Hospital that is of a different nature from the annual ...
Modbury Hospital
core