Results 81 to 90 of about 2,016,887 (339)

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

open access: yesMolecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez   +5 more
wiley   +1 more source

Impact of the Operations Manager's dual role on inventory policy [PDF]

open access: yes, 2007
In modern corporations, the Operations Manager’s role in defining of firm’s strategy is becoming more important. In this paper we describe how firms can use this tendency for Operations Managers to make strategic decisions as a mechanism to prevent ...
Alfaro, José A.   +1 more
core  

Post-test questionnaire - HRI 1 [PDF]

open access: yes, 2018
This questionnaire has been used within the experiments described in a forthcoming publication in order to assess participants' conscious assessment of the quality of the interaction they have experienced with the robot. The questionnaire is based on two
Foerster, Frank
core   +2 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Supply Chain Structure, Inventory Turnover, and Financial Performance: Evidence from Manufacturing Companies in China [PDF]

open access: yes, 2010
Using data collected by the World Bank, we empirically investigate the relationship between Chinese manufacturers’ supply chain attributes, raw material and finished goods inventory turnover, and return on sales.
Chi, Wei   +3 more
core  

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

open access: yesMolecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh   +5 more
wiley   +1 more source

2000 Oregon Winery Report [PDF]

open access: yes, 2001
This statewide survey report on Oregon wineries covers crush, equivalent wine production, inventory and equivalent inventory, and sales. The report also contains some comparisons of data for 1999 and 2000.
Burgess, Laura   +4 more
core   +1 more source

Evaluating the German Inventory Cycle Using Data from the Ifo Business Survey [PDF]

open access: yes
Inventory fluctuations are an important phenomenon in business cycles. However, the preliminary data on inventory investment as published in the German national accounts are tremendously prone to revision and therefore ill-equipped to diagnose the ...
Knetsch, Thomas A.
core   +3 more sources

Use of UAV Photogrammetric Data for Estimation of Biophysical Properties in Forest Stands Under Regeneration

open access: yesRemote Sensing, 2019
The objective of this study was to assess the use of unmanned aerial vehicle (UAV) data for modelling tree density and canopy height in young boreal forests stands.
Stefano Puliti   +2 more
doaj   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

open access: yesMolecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha   +10 more
wiley   +1 more source

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