Results 241 to 250 of about 275,657 (308)

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

open access: yesAdvanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang   +16 more
wiley   +1 more source

The I-Learn Cognition and Behavior program for non-pharmacological treatment of agitation in nursing home residents with neurocognitive disorders: A cluster randomized trial. [PDF]

open access: yesAlzheimers Dement (N Y)
Lourdel C   +18 more
europepmc   +1 more source

Mobile Application as a Digital Therapeutic for Chronic Tinnitus: A Randomized Clinical Trial.

open access: yesJAMA Otolaryngol Head Neck Surg
Wasano K   +6 more
europepmc   +1 more source

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