Results 41 to 50 of about 52,620 (279)

Marine Inventory-Routing Problem for Liquefied Natural Gas under Travel Time Uncertainty [PDF]

open access: yesInternational Journal of Supply and Operations Management, 2020
In this paper modelling maritimeinventory-routing problem for liquefied natural gas (LNG) under uncertainty of travel time is presented. We consider one hypothetical LNG manufacturer in Iran that sells its products in the form of long-term contracts and ...
Sanaz Sheikhtajian   +2 more
doaj   +1 more source

Genetic Algorithm Approach for the Inventory Routing Problem with Backlogging [PDF]

open access: yes
We consider a multi-period inventory-routing problem where a vendor serves multiple geographically dispersed customers who receive units of a single product from a depot with adequate supply.
Sofianopoulou, Stella
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Enhanced multi-task deep reinforcement learning for the integrated inventory-routing problem under VMI mode

open access: yesManagement System Engineering
Effective inventory replenishment and routing are crucial for minimizing supply chain costs and enhancing operational efficiency. In this paper, we focus on the integrated optimization of inventory replenishment and routing problems in Vendor Managed ...
Gang Lu   +3 more
doaj   +1 more source

Multi-Objective Robust Optimization for the Sustainable Location-Inventory-Routing Problem of Auto Parts Supply Logistics

open access: yesMathematics, 2022
A great loss of transportation capacity has been caused in auto parts supply logistics due to the independent transportation from auto parts suppliers (APSs) to the automobile production line (APL).
Ao Lv, Baofeng Sun
doaj   +1 more source

Modeling and solving the multi-period inventory routing problem with constant demand rates [PDF]

open access: yes, 2012
The inventory routing problem (IRP) is one of the challenging optimization problems in supply chain logistics. It combines inventory control and vehicle routing optimization.
Aghezzaf, El-Houssaine, Zhong, Yiqing
core   +1 more source

Complexity of inventory routing problems when routing is easy [PDF]

open access: yesNetworks, 2019
AbstractIn the inventory routing problem (IRP) inventory management and route optimization are combined. The traveling salesman problem (TSP) is a special case of the IRP, hence the IRP is NP‐hard. We investigate how other aspects than routing influence the complexity of a variant of the IRP.
Annelieke C. Baller   +3 more
openaire   +2 more sources

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

open access: yesFEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

open access: yesFEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc   +8 more
wiley   +1 more source

Biomass Native Structure Into Functional Carbon‐Based Catalysts for Fenton‐Like Reactions

open access: yesAdvanced Functional Materials, EarlyView.
This study indicates that eight biomasses with 2D flaky and 1D acicular structures influence surface O types, morphology, defects, N doping, sp2 C, and Co nanoparticles loading in three series of carbon, N‐doped carbon, and cobalt/graphitic carbon. This work identifies how these structural factors impact catalytic pathways, enhancing selective electron
Wenjie Tian   +7 more
wiley   +1 more source

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