Results 101 to 110 of about 4,008,449 (360)

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

open access: yesFEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi   +6 more
wiley   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

Inverses and eigenvalues of diamondalternating sign matrices

open access: yesSpecial Matrices, 2014
An n × n diamond alternating sign matrix (ASM) is a (0, +1, −1)-matrix with ±1 entries alternatingand arranged in a diamond-shaped pattern. The explicit inverse (for n even) or generalized inverse (for nodd) of a diamond ASM is derived.
Catral Minerva   +3 more
doaj   +1 more source

Semidistributive Inverse Semigroups, II [PDF]

open access: yes, 2011
The description by Johnston-Thom and the second author of the inverse semigroups S for which the lattice LJ(S) of full inverse subsemigroups of S is join semidistributive is used to describe those for which (a) the lattice L(S) of all inverse ...
Cheong, Kyeong Hee, Jones, Peter
core   +1 more source

Cognitive Impairment in Multiple Sclerosis: The Role of Clinical and Sociodemographic Factors ‐ A Systematic Review and Meta‐Analysis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment (CI) affects the quality of life in multiple sclerosis (MS). Identifying influencing factors is key to improving CI monitoring. This systematic review and meta‐analysis examines clinical and sociodemographic variables impacting the cognitive screening Symbol Digit Modalities Test (SDMT) performance across MS ...
Katalin Lugosi   +8 more
wiley   +1 more source

Unraveling the rheology of inverse vulcanized polymers [PDF]

open access: gold, 2023
Derek J. Bischoff   +6 more
openalex   +1 more source

Solving inverse problems using data-driven models

open access: yesActa Numerica, 2019
Recent research in inverse problems seeks to develop a mathematically coherent foundation for combining data-driven models, and in particular those based on deep learning, with domain-specific knowledge contained in physical–analytical models.
S. Arridge   +3 more
semanticscholar   +1 more source

Longitudinal Study of Salivary Biomarkers in the Definition of Clinico‐Molecular Progression of Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Longitudinal changes in salivary biomarkers in Parkinson’s disease (PD) from early (T0) to 4‐year follow‐up (T1), quantified by ELISA: oligomeric and total α‐synuclein, total and phosphorylated tau, MAP1LC3B (autophagy), and TNFa (inflammation). Blue arrows indicate direction of change at T1 vs T0 (up = increase; down = decrease).
Maria Ilenia De Bartolo   +13 more
wiley   +1 more source

Limit cycles in models of circular gene networks regulated by negative feedback loops

open access: yesBMC Bioinformatics, 2020
Background The regulatory feedback loops that present in structural and functional organization of molecular-genetic systems and the phenomenon of the regulatory signal delay, a time period between the moment of signal reception and its implementation ...
Vitaly A. Likhoshvai   +2 more
doaj   +1 more source

Altered Dynamic Functional Network Connectivity in Post‐Stroke Aphasia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Previous studies examining post‐stroke aphasia (PSA) patients via resting‐state functional magnetic resonance imaging (rs‐fMRI) have predominantly focused on static functional connectivity. In contrast, the current investigation aims to elucidate the alterations in dynamic functional network connectivity (dFNC) among PSA patients ...
Guihua Xu   +6 more
wiley   +1 more source

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