Results 101 to 110 of about 3,962,404 (360)

Distributive inverse semigroups and non-commutative Stone dualities [PDF]

, 2013
We develop the theory of distributive inverse semigroups as the analogue of distributive lattices without top element and prove that they are in a duality with those etale groupoids having a spectral space of identities, where our spectral spaces are not
Lawson, Mark V, Lenz, Daniel H
core  

Inverse problem for Lagrangian systems on Lie algebroids and applications to reduction by symmetries

, 2015
The language of Lagrangian submanifolds is used to extend a geometric characterization of the inverse problem of the calculus of variations on tangent bundles to regular Lie algebroids.
Barbero-Liñán, María, de Diego, David Martín, Puiggalí, Marta Farré   +2 more
core   +2 more sources

Square matrices with the inverse diagonal property

Kuwait Journal of Science
We identify the class of real square invertible matrices A for which the signs of the diagonal entries of A−1 match those of A, and begin their study. We say such matrices have the inverse diagonal property (IDP).
Susana Furtado, Charles R. Johnson, Carlos Marijuán, Miriam Pisonero   +3 more
doaj   +1 more source

Convexity of the inverse and Moore–Penrose inverse

Linear Algebra and its Applications, 2011
AbstractConvexity properties of the inverse of positive definite matrices and the Moore–Penrose inverse of nonnegative definite matrices with respect to the partial ordering induced by nonnegative definiteness are studied. For the positive definite case null-space characterizations are derived, and lead naturally to a concept of strong convexity of a ...
openaire   +2 more sources

On a Laguerre inversion [PDF]

Communications, Faculty Of Science, University of Ankara Series A1Mathematics and Statistics, 1996
Summary: The existence of some automorphisms on a certain Laguerre plane \(L\) is used to determine the algebraic structure of the projective plane which is a completion of the affine plane \(L_A\) derived at a known point \(A\). In this paper, firstly a special Laguerre automorphism, that is a Laguerre inversion, is defined, and then the set of fixed ...
Rüstem Kaya, Emine Soytürk
openaire   +4 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Solving inverse problems using data-driven models

Acta Numerica, 2019
Recent research in inverse problems seeks to develop a mathematically coherent foundation for combining data-driven models, and in particular those based on deep learning, with domain-specific knowledge contained in physical–analytical models.
S. Arridge, P. Maass, O. Öktem, C. Schönlieb   +3 more
semanticscholar   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity

FEBS Open Bio, EarlyView.
We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda, Melissa Montrose, Akinori Takahashi, Risa Ishida, Sandrine Burriel, Nao Ohmine, Tohru Natsume, Shungo Adachi, Minsoo Kim, Tadashi Yamamoto   +9 more
wiley   +1 more source

Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo

FEBS Open Bio, EarlyView.
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu, Yan Tao, Shan Wu, Yuwen Gong, Youli Zhao, Shaomin Niu, Hui Cheng, You Mu, Na Xu, Ying Wang, Jianzhong Lu, Shanhui Liu, Lanlan Li   +12 more
wiley   +1 more source