Results 101 to 110 of about 1,336,490 (306)
Molecular Oncology, EarlyView.Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis +20 more
wiley +1 more source
Versatile vector tools for efficient protein screening across multiple expression systems
FEBS Open Bio, EarlyView.A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source
Improving rotorcraft survivability to RPG attack using inverse methods [PDF]
, 2009 This paper presents the results of a preliminary investigation of optimal threat evasion strategies for improving the survivability of rotorcraft under attack by rocket propelled grenades (RPGs).
Anderson, D. +3 more
core +1 more source
FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Ultrasonic Proximal Sensing of Pasture Biomass
Remote Sensing, 2019 The optimization of pasture food value, known as ‘biomass’, is crucial in the management of the farming of grazing animals and in improving food production for the future.
Mathew Legg, Stuart Bradley
doaj +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Sparse deterministic approximation of Bayesian inverse problems [PDF]
, 2011 We present a parametric deterministic formulation of Bayesian inverse problems with an input parameter from infinite-dimensional, separable Banach spaces.
A M Stuart +5 more
core +1 more source
Ultrasonic Arrays for Remote Sensing of Pasture Biomass
Remote Sensing, 2019 The profitability of agricultural industries that utilise pasture can be strongly affected by the ability to accurately measure pasture biomass. Pasture height measurement is one technique that has been used to estimate pasture biomass.
Mathew Legg, Stuart Bradley
doaj +1 more source
Convexity of the inverse and Moore–Penrose inverse
Linear Algebra and its Applications, 2011 Based on a re-examination of the convexity results for the inverse of positive definite matrices, and the Moore-Penrose inverse of nonnegative definite matrices, a more general concept of strong convexity is defined which provides additional information on the convexity behaviour and geometry of matrix functions known to be strictly convex.
openaire +2 more sources
Cell surface CD11c as a neutrophil aging marker molecule
FEBS Open Bio, EarlyView.Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source