Results 71 to 80 of about 3,077,553 (314)

Gait Event Prediction Using Surface Electromyography in Parkinsonian Patients

open access: yesBioengineering, 2023
Gait disturbances are common manifestations of Parkinson’s disease (PD), with unmet therapeutic needs. Inertial measurement units (IMUs) are capable of monitoring gait, but they lack neurophysiological information that may be crucial for studying gait ...
Stefan Haufe   +3 more
doaj   +1 more source

Inverse Density as an Inverse Problem: The Fredholm Equation Approach [PDF]

open access: yes, 2013
In this paper we address the problem of estimating the ratio $\frac{q}{p}$ where $p$ is a density function and $q$ is another density, or, more generally an arbitrary function.
Belkin, Mikhail, Que, Qichao
core  

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

Invited review: efficient computation strategies in genomic selection

open access: yesAnimal, 2017
The purpose of this study is review and evaluation of computing methods used in genomic selection for animal breeding. Commonly used models include SNP BLUP with extensions (BayesA, etc), genomic BLUP (GBLUP) and single-step GBLUP (ssGBLUP). These models
I. Misztal, A. Legarra
doaj   +1 more source

Inverse mass matrix via the method of localized lagrange multipliers [PDF]

open access: yes, 2017
An efficient method for generating the mass matrix inverse is presented, which can be tailored to improve the accuracy of target frequency ranges and/or wave contents.
Cho, Sang S.   +5 more
core  

Inverse problem for Lagrangian systems on Lie algebroids and applications to reduction by symmetries

open access: yes, 2015
The language of Lagrangian submanifolds is used to extend a geometric characterization of the inverse problem of the calculus of variations on tangent bundles to regular Lie algebroids.
Barbero-Liñán, María   +2 more
core   +2 more sources

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

Some Remarks on Invertible Refined Neutrosophic Square Matrices [PDF]

open access: yesNeutrosophic Sets and Systems
The main goal of this article is to define the adjoint of refined (resp., n-refined) neutrosophic square matrices, and to study the inverse of these matrices in terms of refined (resp., n-refined) neutrosophic determinants and adjoints. Also, it presents
Ahmad A. Abubaker   +7 more
doaj   +1 more source

Prediction of Protein Tertiary Structure via Regularized Template Classification Techniques

open access: yesMolecules, 2020
We discuss the use of the regularized linear discriminant analysis (LDA) as a model reduction technique combined with particle swarm optimization (PSO) in protein tertiary structure prediction, followed by structure refinement based on singular value ...
Óscar Álvarez-Machancoses   +2 more
doaj   +1 more source

A DIA‐MS‐based proteomics approach to find potential serum prognostic biomarkers in glioblastoma patients

open access: yesMolecular Oncology, EarlyView.
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy