Results 81 to 90 of about 3,872,829 (369)
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach+8 more
wiley +1 more source
In this paper, we study periodic tridiagonal Toeplitz matrices with perturbed corners. By using some matrix transformations, the Schur complement and matrix decompositions techniques, as well as the Sherman-Morrison-Woodbury formula, we derive explicit ...
Yunlan Wei+3 more
doaj +1 more source
Gait Event Prediction Using Surface Electromyography in Parkinsonian Patients
Gait disturbances are common manifestations of Parkinson’s disease (PD), with unmet therapeutic needs. Inertial measurement units (IMUs) are capable of monitoring gait, but they lack neurophysiological information that may be crucial for studying gait ...
Stefan Haufe+3 more
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A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul+11 more
wiley +1 more source
In this work, we studied a Ti-Nb-Zr-Sn system for exploring novel composition and temperatures that will be helpful in maximizing the stability of β phase while minimizing the formation of α” and ω-phase. The Ti-Nb-Zr-Sn system is free of toxic elements.
Rajesh Jha, George S. Dulikravich
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The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli+15 more
wiley +1 more source
Resistance Distance in the Double Corona Based on R-Graph
Let G 0 be a connected graph on n vertices and m edges. The R-graph R ( G 0 ) of G 0 is a graph obtained from G 0 by adding a new vertex corresponding to each edge of G 0 and by joining each new vertex to the end
Li Zhang+3 more
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Prediction of Protein Tertiary Structure via Regularized Template Classification Techniques
We discuss the use of the regularized linear discriminant analysis (LDA) as a model reduction technique combined with particle swarm optimization (PSO) in protein tertiary structure prediction, followed by structure refinement based on singular value ...
Óscar Álvarez-Machancoses+2 more
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Inverse Density as an Inverse Problem: The Fredholm Equation Approach [PDF]
In this paper we address the problem of estimating the ratio $\frac{q}{p}$ where $p$ is a density function and $q$ is another density, or, more generally an arbitrary function.
Belkin, Mikhail, Que, Qichao
core
Gut alterations in a chronic kidney disease rat model with diet‐induced vascular calcification
Chronic kidney disease (CKD) patients often suffer from intestinal and/or mineral and bone disorders. Using a rat model, we showed that uremic vascular calcification is associated with gut barrier alterations (decreased gut mucus production and Nlrp6 gene expression, increased gut inflammation), and plasma retention of gut‐origin uremic toxins (indoxyl
Piotr Bartochowski+13 more
wiley +1 more source