Results 71 to 80 of about 2,012,623 (293)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Different methods of equilibrium moisture content determination [PDF]

Journal on Processing and Energy in Agriculture, 2017
In this paper, a faster and easier way, in comparison with classical methods, to determine the equilibrium moisture content in food materials is shown.
Lutovska Monika, Mitrevski Vangelce, Pavkov Ivan, Babić Mirko, Mijakovski Vladimir, Geramitcioski Tale, Stamenković Zoran   +6 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

A Novel Hybrid Approach for Numerical Modeling of the Nucleating Flow in Laval Nozzle and Transonic Steam Turbine Blades

Energies, 2017
In the present research, considering the importance of desirable steam turbine design, improvement of numerical modeling of steam two-phase flows in convergent and divergent channels and the blades of transonic steam turbines has been targeted. The first
Edris Yousefi Rad, Mohammad Reza Mahpeykar   +1 more
doaj   +1 more source

INVERSE-FREE NEWTON'S METHOD

Journal of Applied Analysis & Computation
Summary: We present a modification of Newton's method for finding a zero of a multivariable function without an inverse of a matrix in a recurrence. The aim of this paper is twofold: demonstrating at least quadratic convergence of a Newton-type method avoiding matrix inversion under standard assumptions, and then comparing modified and classical Newton'
Massalski, Marcin, Nockowska-Rosiak, Magdalena   +1 more
openaire   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

A coupling method of direct and inverse heat conduction problem for transient temperature calculation of the supercharged boiler drum

Journal of Thermal Science and Technology, 2016
The supercharged boiler drum is partly surrounded by the furnace flue gas and hot air, and it's difficult to precisely determine the temperature field from the direct method.
Enhui SUN, Bin LI, Liangxiao SHI, Feng CHEN   +3 more
doaj   +1 more source

Optimization and Modeling of Sound-Absorption Properties of Natural Fibers for Acoustical Application

Journal of Natural Fibers, 2022
Kenaf fibers have long been utilized because of their remarkable properties, such as availability, durability, and strength. Recently, they have also been used as sound-absorbing composites for noise control purposes.
Seyed Ehsan Samaei, Ebrahim Taban, Umberto Berardi, Seyyed Mohammad Mousavi, Mohammad Faridan, AsilianMahabadi Hassan   +5 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Reconstruction of Aircraft Engine Noise Source using Beamforming and Compressive Sensing

IEEE Access, 2018
A novel signal processing approach is proposed for sensor arrays to reconstruct spinning modal noise source from scattered sound wave measurements outside the jet flow downstream of an unflanged duct.
Wenjun Yu, Xun Huang
doaj   +1 more source