Results 41 to 50 of about 14,778,763 (297)

MATHEMATICAL MODELS FOR CHROMOSOMAL INVERSIONS [PDF]

open access: yesGenetics, 1967
INCE a formal characterization of the nature of inversions has not been made to date, this paper will hypothesize mathematical models for the occurrence of inversions of various lengths, obtain the associated probability distributions of lengths and midpoints of chromosomal inversions, and compare the hypothesized models with two sets of data.
W T, Federer, R G, Steel, B, Wallace
openaire   +2 more sources

Inverzná optimalizácia v obehových rozvrhoch autobusov [PDF]

open access: yesTrendy v podnikání, 2016
In this paper we study nontraditional model which can occur for the bus scheduling problems. It is motivated by answer to the question: At what minimum shortening of the driving time in some sections of the transport network will happen that an existing ...
Štefan Peško
doaj  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Inverse modeling of European CH4 emissions: sensitivity to the observational network [PDF]

open access: yes, 2009
Inverse modeling is widely employed to provide “top-down” emission estimates using atmospheric measurements. Here, we analyze the dependence of derived CH4 emissions on the sampling frequency and density of the observational surface network, using the ...
Bergamaschi, P.   +9 more
core   +2 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Improving rotorcraft survivability to RPG attack using inverse methods [PDF]

open access: yes, 2009
This paper presents the results of a preliminary investigation of optimal threat evasion strategies for improving the survivability of rotorcraft under attack by rocket propelled grenades (RPGs).
Anderson, D.   +3 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

A REE Inverse Model From Bulk Distribution Coefficients and Boundary Conditions: Results for Shield and Rejuvenated Stage Hawaiian Volcanoes

open access: yesGeochemistry, Geophysics, Geosystems
A major challenge in mantle geochemistry is determining the source composition and melt fraction involved in melting. We provide a new Rare‐Earth Element (REE) inverse model that provides source concentration, source and melt mineral modes, and melt ...
M. J. Carr, M. D. Feigenson, E. Gazel
doaj   +1 more source

Trajectory Control of Flexible Manipulators Using Forward and Inverse Models with Neural Networks

open access: yesVibration
This study explores trajectory control in flexible manipulators using neural-network-based forward and inverse modeling. Unlike traditional approaches that enhance precision by increasing structural rigidity—often at the cost of added weight and energy ...
Minoru Sasaki   +3 more
doaj   +1 more source

An Inverse Model for Raindrop Size Distribution Retrieval with Polarimetric Variables

open access: yesRemote Sensing, 2018
This paper proposes an inverse model for raindrop size distribution (DSD) retrieval with polarimetric radar variables. In this method, a forward operator is first developed based on the simulations of monodisperse raindrops using a T-matrix method, and ...
Guang Wen   +3 more
doaj   +1 more source

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