Results 51 to 60 of about 142,726 (269)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Remote Sensing, 2018 L-band radiometer measurements were performed at the Selhausen remote sensing field laboratory (Germany) over the entire growing season of a winter wheat stand.
Thomas Meyer +3 more
doaj +1 more source
Generative Modelling With Inverse Heat Dissipation
CoRR, 2022 While diffusion models have shown great success in image generation, their noise-inverting generative process does not explicitly consider the structure of images, such as their inherent multi-scale nature. Inspired by diffusion models and the empirical success of coarse-to-fine modelling, we propose a new diffusion-like model that generates images ...
Solin Arno +2 more
openaire +3 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Atmosphere, 2016 Observational constraints to biomass burning (BB) NOx emissions as provided by satellite measurements of nitrogen dioxide (NO2) critically depend on quantitative assumptions regarding the atmospheric NOx lifetime.
Evgeny V. Berezin +2 more
doaj +1 more source
Mathematics, 2022 The calcium leaching effect inevitably increases the grout curtain hydraulic conductivity. It is diffucult to sample and obtain the leaching-related calculation parameters for deep-buried grout curtains.
Kailai Zhang +4 more
doaj +1 more source
Spin Model for Inverse Melting and Inverse Glass Transition [PDF]
Physical Review Letters, 2004 A spin model that displays inverse melting and inverse glass transition is presented and analyzed. Strong degeneracy of the interacting states of an individual spin leads to entropic preference of the "ferromagnetic" phase, while lower energy associated with the non-interacting states yields a "paramagnetic" phase as temperature decreases.
Schupper, Nurith, Shnerb, Nadav M.
openaire +3 more sources
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Discovering Influencers in Opinion Formation Over Social Graphs
IEEE Open Journal of Signal Processing, 2023 The adaptive social learning paradigm helps model how networked agents are able to form opinions on a state of nature and track its drifts in a changing environment.
Valentina Shumovskaia +3 more
doaj +1 more source