Results 61 to 70 of about 142,726 (269)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Applied SciencesSoil consolidation modeling is essential for estimating settlement and pore-water pressure dissipation, but analytical solutions are limited for layered soils with complex drainage and interface conditions.
Yang Chen, De’an Sun, Jie Zhou
doaj +1 more source
Inverse procedural modeling of facade layouts [PDF]
ACM Transactions on Graphics, 2014 In this paper, we address the following research problem: How can we generate a meaningful split grammar that explains a given facade layout? To evaluate if a grammar is meaningful, we propose a cost function based on the description length and minimize this cost using an approximate dynamic programming framework.
Fuzhang Wu +4 more
openaire +2 more sources
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Applied SciencesThis study presents the development of a discrete algorithm for interpreting ground-penetrating radar (GPR) data in vertically inhomogeneous media for the diagnostics of road structures. Experimental data were obtained using an OKO-2 GPR system, followed
Kazizat Iskakov +5 more
doaj +1 more source
, 1998 Publication in the conference proceedings of EUSIPCO, Rhodes, Greece ...
David Declercq +2 more
openaire +3 more sources
3D inverse dynamic modeling of strands [PDF]
ACM SIGGRAPH 2011 Posters, 2011 In this poster, we propose a new method to automatically and consistently convert 3D splines into dynamic rods at rest under gravity, bridging the gap between the modeling of 3D strands (such as hair, plants) and their physics-based animation.
Derouet-Jourdan, Alexandre +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source