Results 41 to 50 of about 155,658 (262)

Comparative Analysis of Starlight Occultation Data Processing

open access: yesAtmosphere, 2023
In order to improve the inversion accuracy of stellar occultation data and to provide a reference for the selection of inversion methods with higher accuracy in the future, this study compared and analyzed the inversion effects of two different methods ...
Mingchen Sun   +5 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

High-Resolution Seismic Characterization of Gas Hydrate Reservoir Using Wave-Equation-Based Inversion

open access: yesEnergies, 2022
The high-resolution seismic characterization of gas hydrate reservoirs plays an important role in the detection and exploration of gas hydrate. The conventional AVO (amplitude variation with offset) method is based on a linearized Zoeppritz equation and ...
Jie Shao   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Distributed Fiber Optic Sensing for Fracture Geometry Inversion Using All Time Steps Data

open access: yesSensors
As an advanced real-time monitoring technique, optic fiber downhole sensing has been widely applied in monitoring fracture propagation during hydraulic fracturing.
Shaohua You   +7 more
doaj   +1 more source

Seismic Waveform Inversion Using the Finite-Difference Contrast Source Inversion Method

open access: yesJournal of Applied Mathematics, 2014
This paper extends the finite-difference contrast source inversion method to reconstruct the mass density for two-dimensional elastic wave inversion in the framework of the full-waveform inversion.
Bo Han   +3 more
doaj   +1 more source

Filtering Methods for Coupled Inverse Problems

open access: yesSIAM Journal on Applied Dynamical Systems, 2023
We are interested in ensemble methods to solve multi-objective optimization problems. An ensemble Kalman method is proposed to solve a formulation of the nonlinear problem using a weighted function approach. An analysis of the mean field limit of the ensemble method yields an explicit update formula for the weights. Numerical examples show the improved
Michael Herty, Elisa Iacomini
openaire   +4 more sources

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

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