Results 61 to 70 of about 155,658 (262)
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Localization of areas of increased vibroactivity by means of the inverse method
Archives of Acoustics, 2014 Increased possibilities of parallel acquiring data and transforming them effectively together with the improvement of calculation tools made the inverse methods more important.
Lesław STRYCZNIEWICZ
doaj
Progress and Challenge of Optical Remote Sensing Inversion on Soil Moisture
Renmin Zhujiang, 2021 Soil moisture is an important parameter for influencing the land surface rainfall and runoff,and a key parameter for understanding the interaction of water and energy between the earth and the atmosphere.Monitoring of this parameter is of great ...
QIN Xiangdong, PANG Zhiguo, JIANG Wei
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Optimization Methods for Inverse Problems [PDF]
, 2019 Optimization plays an important role in solving many inverse problems. Indeed, the task of inversion often either involves or is fully cast as a solution of an optimization problem. In this light, the mere non-linear, non-convex, and large-scale nature of many of these inversions gives rise to some very challenging optimization problems.
Ye, Nan +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
f(R) Cosmology, analytical inversion method
Nuclear Physics BInflation, the rapid expansion of spacetime in the early universe, provides an elegant resolution to several fundamental cosmological problems. Among various theoretical approaches, f(R) gravity offers a minimal yet powerful extension of General ...
David Senjaya
doaj +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Comparison of deterministic and stochastic approaches to crosshole seismic travel-time inversions
Earth and Planetary Physics, 2019 The Bayesian inversion method is a stochastic approach based on the Bayesian theory. With the development of sampling algorithms and computer technologies, the Bayesian inversion method has been widely used in geophysical inversion problems.
YanZhe Zhao, YanBin Wang
doaj +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source