Structure of an LGR dimer, an evolutionary predecessor of glycoprotein hormone receptors [PDF]
Nature CommunicationsGlycoprotein hormones (GpHs) produced in the human pituitary act through receptors (GpHRs) in the gonads to support reproduction and in the thyroid for metabolism.
Zhen Gong +8 more
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Developmental effects of sulfated thyroid hormones in sea urchin skeletogenesis suggest activation of non-canonical thyroid hormone signaling pathway [PDF]
Frontiers in EndocrinologyThyroid hormones (THs) are essential regulators of metabolism, homeostasis, and development in metazoans. The canonical genomic pathway involves THs binding to nuclear thyroid hormone receptors (NTHRs), which modulate gene expression in vertebrates.
Katherine Tieman, Andreas Heyland
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Role of StAR Gene in Sex Steroid Hormone Regulation and Gonadal Development in Ark Shell Scapharca broughtonii [PDF]
BiologyThis study elucidates the role of the steroidogenic acute regulatory protein (StAR) in sex steroid hormone dynamics and the gonadal development of the commercially important marine bivalve ark shell Scapharca broughtonii.
Wenjing Wang +9 more
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Invertebrate Gonadotropin-Releasing Hormone-Related Peptides and Their Receptors: An Update [PDF]
Frontiers in Endocrinology, 2017 Gonadotropin-releasing hormones (GnRHs) play pivotal roles in reproductive functions via the hypothalamus, pituitary, and gonad axis, namely, HPG axis in vertebrates.
Tsubasa Sakai +5 more
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Encyclopedia, 2021 Ecdysteroid: member of a class of polyhydroxylated steroids found in invertebrate animals (zooecdysteroids; moulting hormones), plants (phytoecdysteroids) and fungi (mycoecdysteroids). Over 500 structural analogues are currently known.
René Lafont +2 more
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Unconventional Actions of Glycoprotein Hormone Subunits: A Comprehensive Review
Frontiers in Endocrinology, 2021 The glycoprotein hormones (GPH) are heterodimers composed of a common α subunit and a specific β subunit. They act by activating specific leucine-rich repeat G protein-coupled receptors. However, individual subunits have been shown to elicit responses in
Bruno Querat
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Hormonal Regulation of Programmed Cell Death in Sea Urchin Metamorphosis
Frontiers in Ecology and Evolution, 2021 Programmed cell death (PCD) has been identified as a key process in the metamorphic transition of indirectly developing organisms such as frogs and insects.
Hannah Wynen, Andreas Heyland
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Steroid hormone regulation of innate immunity in Drosophila melanogaster.
PLoS Genetics, 2023 Endocrine signaling networks control diverse biological processes and life history traits across metazoans. In both invertebrate and vertebrate taxa, steroid hormones regulate immune system function in response to intrinsic and environmental stimuli ...
Scott A Keith
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A toxin-based approach to neuropeptide and peptide hormone discovery
Frontiers in Molecular Neuroscience, 2023 Peptide hormones and neuropeptides form a diverse class of bioactive secreted molecules that control essential processes in animals. Despite breakthroughs in peptide discovery, many signaling peptides remain undiscovered.
Thomas Lund Koch +10 more
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Fat Body—Multifunctional Insect Tissue
Insects, 2021 The biodiversity of useful organisms, e.g., insects, decreases due to many environmental factors and increasing anthropopressure. Multifunctional tissues, such as the fat body, are key elements in the proper functioning of invertebrate organisms and ...
Patrycja Skowronek +2 more
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