Results 61 to 70 of about 31,741 (316)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Considerations on Combining Unfolding Inverters with Partial Power Regulators in Battery–Grid Interface Converters

Energies
The application of electrochemical cells as a source unit of electrical energy is rapidly growing—used in electric vehicles and other electric mobility devices, as well as in energy supply systems—as energy storage, often together with renewable energy ...
Ilya A. Galkin, Rodions Saltanovs, Alexander Bubovich, Andrei Blinov, Dimosthenis Peftitsis   +4 more
doaj   +1 more source

On invertibility and positive invertibility of matrices

Linear Algebra and its Applications, 2001
Let \(A=[a_{ij}]\) be an \(n\times n\) complex matrix whose diagonal entries are all nonzero. For each \(k\) define \[ \tilde{v}_{k}:=\max\left\{\left|a_{jk}\right|:j=1,\dots ,k-1\right\} \text{ and }\tilde{w}_{k}:=\max\left\{ \left|a_{jk}\right|:j=k+1,\dots ,n-1\right\} \] and put \[ m:=\prod_{k=2}^{n}\left( 1+\frac{\tilde{v}_{k}}{\left|a_{kk}\right|}\
openaire   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Sistemas fotovoltaicos conectados a redes de distribuição urbanas: sua influência na qualidade da energia elétrica e análise dos parâmetros que possam afetar a conectividade [PDF]

, 2012
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia Civil, Florianópolis, 2010Este trabalho aborda a interação entre os inversores de sistemas fotovoltaicos conectados à rede elétrica ...
Urbanetz Junior, Jair
core  

Pulse-Width Modulation of Z-Source Inverters

, 2005
Z-Source inverters have recently been proposed as an alternative power conversion concept as they have both voltage buck and boost capabilities. These inverters use a unique impedance network, coupled between the power source and converter circuit, to ...
Chua, G.T., Vilathgamuwa, Mahinda, Loh, P.C., Lai, Y.S., Li, Y.   +4 more
core   +1 more source

State feedback control of multilevel inverters for DSTATCOM applications [PDF]

, 2007
In this paper, load compensation using multilevel inverter-based distribution static compensator (DSTATCOM) is presented. The DSTATCOM is connected to a three-phase four-wire (3p4w) distribution system.
Ghosh, A, Ghosh, Arindam, Shukla, A, Shukla, Anshuman, Joshi, A, Joshi, Avinash   +5 more
core   +1 more source

Rational distribution of excess regenerative energy in electric transport systems on the basis of fuzzy logic application [PDF]

Archives of Transport, 2017
Purpose. To develop the fuzzy model of distribution of excess regenerative energy in traction and external power supply systems allowing to exercise effective operation of the power equipment. Relevance.
Oleg Sablin, Valeriy Kuznetsov, Victor Shinkarenko, Alexander Ivanov   +3 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

A Noninvasive and Robust Diagnostic Method for Open-Circuit Faults of Three-Level Inverters

IEEE Access, 2019
This paper proposes a noninvasive switch open-circuit (OC) fault diagnosis method for a three-level inverter based on voltage detection. Under both healthy and faulty operation, the possible values of two line voltages are analyzed, and the waveforms are
Xun Wu, Te-Fang Chen, Shu Cheng, Tianjian Yu, Chaoqun Xiang, Kaidi Li   +5 more
doaj   +1 more source