Results 41 to 50 of about 968 (290)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Pilot protection scheme for transmission line of a hybrid HVDC system based on polarity characteristics of current and voltage fault components

The Journal of Engineering, 2019
A hybrid high-voltage direct current (HVDC) system comprises a line commutated converter (LCC) at the rectifier side and a voltage source converter (VSC) at the inverter side, combining advantages of both LCC and VSC systems.
Yanting Wang, Baohui Zhang, Baohui Zhang, Shaojie Cheng   +3 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Influence of ankle invertor muscle fatigue on workload of the lower extremity joints during single-leg landing in the sagittal and frontal planes [PDF]

Background: Insufficient rigidity of the foot owing to its ligaments and muscles can decrease the attenuation of the ground reaction force during landing.
Ichihashi, Noriaki, Komatsu, Tomoyo, Tateuchi, Hiroshige, Hirono, Tetsuya, Yamagata, Momoko   +4 more
core   +1 more source

DIP BEHAVIOUR OF GRID CONNECTED INVERTORS [PDF]

, 2020
The environmental awareness has led to a considerably increasing demand for renewable ...
Colin Debruyne, Jan Desmet, Kurt Stockman, Bart Verhelst   +3 more
core  

Foot and leg muscle weakness in people with midfoot osteoarthritis [PDF]

, 2021
Objective To compare foot and leg muscle strength in people with symptomatic midfoot osteoarthritis (OA) with asymptomatic controls, and to determine the association between muscle strength, foot pain and disability.
Arnold, JB, Anthony C. Redmond, Anne‐Maree Keenan, Redmond, A.C., Keenan, A, Hill, CL, Redmond, AC, Catherine L. Hill, Andrew J. Grainger, Grainger, AJ, Hill, C.L., Keenan, A.-M., John B. Arnold, Arnold, J.B., Jill Halstead, Halstead, J., Grainger, A.J., Halstead, J   +17 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Detection and classification of turn fault and high-resistance connection fault in inverter-fed permanent magnet machines based on high-frequency signals

The Journal of Engineering, 2019
Winding turn fault and high-resistance connection (HRC) fault will lead to different consequences and require different mitigation actions. In this study, the differentiating features between a turn fault and HRC fault are analysed and compared in a ...
Rongguang Hu, Jiabin Wang, Jiabin Wang, Andrew Mills, Ellis Chong, Zhigang Sun   +5 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source