Results 51 to 60 of about 137,542 (360)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Reduced-order dynamic model for droop-controlled inverter/converter-based low-voltage hybrid AC/DC microgrids – Part 2: DC sub-microgrid and power exchange

open access: yesIET Smart Grid, 2018
This study focuses on reduced-order dynamical modelling of droop controlled converter-based DC sub-microgrid (MG) in a hybrid AC/DC MG. In hybrid MGs, electrical power is exchanged between the AC and DC sub-MGs by a bidirectional AC/DC converter.
Arsalan Rasoolzadeh   +2 more
doaj   +1 more source

A simplified space vector pulse width modulation method for a three‐level four‐leg inverter considering the neutral point potential balance

open access: yesIET Power Electronics, 2023
This paper presents a simple three‐dimensional space vector modulation method in ghγ coordinates for a three‐level four‐leg neutral‐point‐clamped inverter.
Zhi Zhang   +5 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Architecture of urban rail transit power supply based on PET braking energy feedback

open access: yesThe Journal of Engineering, 2019
In recent years, the urban rail transit has a great development in many cities of China. It is important to keep the DC transit grid strong and the power transmitted/power transmission high quality.
Hao Liu, Zedong Zheng, Zheng Xu
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Stability analysis of distributed generation grid-connected inverter

open access: yesThe Journal of Engineering, 2019
With the distributed new energy power generation increased, the power grid system becomes more and more complex, leading to its stability more likely to be affected. Among them, the resonance caused by impedance mismatch is particularly critical.
Xuemei Zheng   +4 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Research on the strategy of cooperative control between photovoltaic grid-connected and reactive power compensation technology

open access: yesThe Journal of Engineering, 2019
When connecting a large number of generating sets into power grid, there will be the harmonic wave generated in power grid causing voltage and current distortion, which affects power quality seriously.
Zhigang Li   +3 more
doaj   +1 more source

Impact of advanced inverter functions on low‐voltage power grids

open access: yesIET Energy Systems Integration, 2021
In today's power grid, a great number of inverter‐based distributed energy resources (DERs) are connected and are mainly designed to supply power without considering the voltage and frequency deviations of the grid.
Arjen Mentens   +5 more
doaj   +1 more source

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